Assessment of Cardiovascular Risk Factors in Post-Menopausal Females
Creators
- 1. Assistant Professor, Department of Physiology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly
- 2. Assistant Professor, Department of General Medicine, Autonomous State Medical College, Shahjahanpur
- 3. Professor, Department of Cardiology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly
- 4. Professor, Department of General Medicine, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly
Description
Introduction: Menopause is not a disease, but a physiologic phase of a woman’s life, due to the changes of their hormonal status. Menopause is a physiological period of a woman’s life during which she lacks menstruation continuously for 12 months. Lives have been extended with improved diagnosis and treatment modalities, and women spend 20-30 years in the post-menopausal period. Fastidious symptoms may be associated with changes in the metabolism together with new cardiovascular risk factors, particularly aggressive for the female cardiovascular system, unprepared because of the protection due to the fertile period. Changes of the lipid profile, obesity, hypertension, glucose intolerance and diabetes mellitus may intervene as severe risk factors. Cardiovascular disease represents therefore the most frequent cause of mortality and morbidity also in the female gender more than cancer. These changes are often ignored in Indian scenarios which are the important determinant of cardiovascular risk factors. Early diagnosis of these factors helps in early treatment and thus helps in a healthy ageing. Objectives: Assessment of cardiovascular risk factor in Postmenopausal women. Methods: Total 150 females were selected from general population with the age between 25-65 years. They were divided into two group namely premenopausal and postmenopausal women with each group having 75 subjects. 2D echocardiography was performed by standard methods. Blood sample was taken for Lipid profile and blood sugar in fasting state. Results were compared using student t test. Results: Age and BMI shows significant difference in Postmenopausal women. Pulse & Blood Pressure profile shows a significant difference. IVSTd, IVSTs and PWT show significant difference in postmenopausal females. LVM and LVMI were statistically significant in Postmenopausal females. Fasting blood sugar, Serum Cholesterol, triglyceride, HDL and LDL shows statistically significant difference. Conclusion: Potentially, adverse changes in LVM, LVMI, fasting blood sugar and lipid profile in postmenopausal women of the study group remark that this group of women is at increased risk of having complications associated with cardiovascular disease in near future. Early and timely detection and primary prevention can avoid morbidity and mortality in this high risk population. Early diagnosis of changes in postmenopausal women will help us to take preventive measures early so as to reduce cardiac morbidity and mortality and to make healthy ageing.
Abstract (English)
Introduction: Menopause is not a disease, but a physiologic phase of a woman’s life, due to the changes of their hormonal status. Menopause is a physiological period of a woman’s life during which she lacks menstruation continuously for 12 months. Lives have been extended with improved diagnosis and treatment modalities, and women spend 20-30 years in the post-menopausal period. Fastidious symptoms may be associated with changes in the metabolism together with new cardiovascular risk factors, particularly aggressive for the female cardiovascular system, unprepared because of the protection due to the fertile period. Changes of the lipid profile, obesity, hypertension, glucose intolerance and diabetes mellitus may intervene as severe risk factors. Cardiovascular disease represents therefore the most frequent cause of mortality and morbidity also in the female gender more than cancer. These changes are often ignored in Indian scenarios which are the important determinant of cardiovascular risk factors. Early diagnosis of these factors helps in early treatment and thus helps in a healthy ageing. Objectives: Assessment of cardiovascular risk factor in Postmenopausal women. Methods: Total 150 females were selected from general population with the age between 25-65 years. They were divided into two group namely premenopausal and postmenopausal women with each group having 75 subjects. 2D echocardiography was performed by standard methods. Blood sample was taken for Lipid profile and blood sugar in fasting state. Results were compared using student t test. Results: Age and BMI shows significant difference in Postmenopausal women. Pulse & Blood Pressure profile shows a significant difference. IVSTd, IVSTs and PWT show significant difference in postmenopausal females. LVM and LVMI were statistically significant in Postmenopausal females. Fasting blood sugar, Serum Cholesterol, triglyceride, HDL and LDL shows statistically significant difference. Conclusion: Potentially, adverse changes in LVM, LVMI, fasting blood sugar and lipid profile in postmenopausal women of the study group remark that this group of women is at increased risk of having complications associated with cardiovascular disease in near future. Early and timely detection and primary prevention can avoid morbidity and mortality in this high risk population. Early diagnosis of changes in postmenopausal women will help us to take preventive measures early so as to reduce cardiac morbidity and mortality and to make healthy ageing.
Files
IJPCR,Vol15,Issue5,Article218.pdf
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Additional details
Dates
- Accepted
-
2023-05-20
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue5,Article218.pdf
- Development Status
- Active
References
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