The Value of Hyperbilirubinemia in the Diagnosis of Acute Appendicitis
Authors/Creators
- 1. Assistant Professor, Department of General Surgery, Krishna Mohan Medical College & Hospital, Pali Dungra, Sonkh Road, Mathura
Description
Background: Appendix inflammation is referred to as appendicitis. It’s a medical emergency that almost always necessitates appendix removal surgery as soon as feasible. There is currently no reliably specific marker for acute appendicitis. Although C-reactive protein (CRP) is frequently utilized in the assessment of suspected appendicitis, its specificity varies significantly among studies and can only be dramatically elevated if appendiceal perforation occurs. Material and Method: A general of two hundred sufferers had pressing appendicectomies completed for the duration of the observe length and 172 have been protected withinside the observe. Patients have been divided into 4 agencies in line with their histology findings. Result: Mean bilirubin levels were higher in patients with simple acute appendicitis than in those with an uninflamed appendix (18.7 vs. 14.5 mol/l, p<0.001), and they also had noticeably more patients with hyperbilirubinemia at the time of admission (30% vs. 12%, p<0.001). Patients with hyperbilirubinemia are more than three times as likely to experience simple acute appendicitis as those without it (odds ratio [OR]: 3.25). With a 91% positive predictive value, hyperbilirubinaemia exhibited an 88% specificity for simple acute appendicitis. Conclusion: A precise diagnostic for acute appendicitis with a high positive predictive value is bilirubin. It is also a useful sign of those who are more prone to have gangrene or an appendiceal perforation. When evaluating individuals with suspected acute appendicitis, bilirubin should be utilised in conjunction with clinical examination and other laboratory findings.
Abstract (English)
Background: Appendix inflammation is referred to as appendicitis. It’s a medical emergency that almost always necessitates appendix removal surgery as soon as feasible. There is currently no reliably specific marker for acute appendicitis. Although C-reactive protein (CRP) is frequently utilized in the assessment of suspected appendicitis, its specificity varies significantly among studies and can only be dramatically elevated if appendiceal perforation occurs. Material and Method: A general of two hundred sufferers had pressing appendicectomies completed for the duration of the observe length and 172 have been protected withinside the observe. Patients have been divided into 4 agencies in line with their histology findings. Result: Mean bilirubin levels were higher in patients with simple acute appendicitis than in those with an uninflamed appendix (18.7 vs. 14.5 mol/l, p<0.001), and they also had noticeably more patients with hyperbilirubinemia at the time of admission (30% vs. 12%, p<0.001). Patients with hyperbilirubinemia are more than three times as likely to experience simple acute appendicitis as those without it (odds ratio [OR]: 3.25). With a 91% positive predictive value, hyperbilirubinaemia exhibited an 88% specificity for simple acute appendicitis. Conclusion: A precise diagnostic for acute appendicitis with a high positive predictive value is bilirubin. It is also a useful sign of those who are more prone to have gangrene or an appendiceal perforation. When evaluating individuals with suspected acute appendicitis, bilirubin should be utilised in conjunction with clinical examination and other laboratory findings.
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IJTPR,Vol11,Issue6,Article28.pdf
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Additional details
Dates
- Accepted
-
2021-10-28
Software
References
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