Effects of Phototherapy on the Serum Magnesium Level in Neonates with Indirect Hyperbilirubinemia: A Prospective Cohort Study
Authors/Creators
- 1. Senior Resident, Department of Pediatrics, AIIMS, New Delhi, India
- 2. Senior Resident, Department of Pediatrics, Kalawati Saran Children Hospital, New Delhi, India.
Description
Abstract
Aim: The aim of the present study was to determine the effect of phototherapy on serum
magnesium level in term neonates with hyperbilirubinemia.
Material & Methods: A prospective hospital‑based comparative study was conducted on 100
eligible neonates admitted in Department of Pediatrics, AIIMS, New Delhi, receiving
phototherapy from January 2019 to December 2019. After approval of the ethical committee,
informed consent was obtained from the parents of the selected neonates. This study included
100 full‑term neonates who were subjected to phototherapy for treating neonatal
hyperbilirubinemia according to the guidelines of the American Academy of Pediatrics.
Results: Our study included 100 full‑term neonates with jaundice who received phototherapy
for treating neonatal indirect hyperbilirubinemia, comprising 60 (60%) males, and 40 (40%)
females, with the mean gestational age of 38 ± 0.7 weeks and mean postnatal age of 5.4 ± 1.3
days. There were 32 (32%) neonates delivered by normal vaginal delivery and 68 (68%)
neonates delivered by cesarean section. Mean birth weight was 3.1 kg. The mean difference of
jaundice onset age, intrauterine age, admission weight and mother’s age were not significant.
The amount of total serum bilirubin decreases in all groups. The serum total magnesium level
and its changes were reported in three groups before and after phototherapy.
Conclusion: In the present study, the serum magnesium level showed a significant reduction
only in the double phototherapy method and remained in the normal range in the other two
groups. On the other hand, in all three treatment groups, the level of serum magnesium before
the treatment was normal and did not increase significantly
Abstract (English)
Abstract
Aim: The aim of the present study was to determine the effect of phototherapy on serum
magnesium level in term neonates with hyperbilirubinemia.
Material & Methods: A prospective hospital‑based comparative study was conducted on 100
eligible neonates admitted in Department of Pediatrics, AIIMS, New Delhi, receiving
phototherapy from January 2019 to December 2019. After approval of the ethical committee,
informed consent was obtained from the parents of the selected neonates. This study included
100 full‑term neonates who were subjected to phototherapy for treating neonatal
hyperbilirubinemia according to the guidelines of the American Academy of Pediatrics.
Results: Our study included 100 full‑term neonates with jaundice who received phototherapy
for treating neonatal indirect hyperbilirubinemia, comprising 60 (60%) males, and 40 (40%)
females, with the mean gestational age of 38 ± 0.7 weeks and mean postnatal age of 5.4 ± 1.3
days. There were 32 (32%) neonates delivered by normal vaginal delivery and 68 (68%)
neonates delivered by cesarean section. Mean birth weight was 3.1 kg. The mean difference of
jaundice onset age, intrauterine age, admission weight and mother’s age were not significant.
The amount of total serum bilirubin decreases in all groups. The serum total magnesium level
and its changes were reported in three groups before and after phototherapy.
Conclusion: In the present study, the serum magnesium level showed a significant reduction
only in the double phototherapy method and remained in the normal range in the other two
groups. On the other hand, in all three treatment groups, the level of serum magnesium before
the treatment was normal and did not increase significantly
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IJCPR,Vol15,Issue6,Article38.pdf
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Additional details
Dates
- Accepted
-
2023-05-20