Published August 30, 2023 | Version v1
Journal article Open

Study to Identify Role of Preoperative Bilirubin Level in Predicting the Severity of Acute Appendicitis

  • 1. Senior Resident, Department of General Surgery, Himalayan Institute of Medical Sciences, Dehradun, India
  • 2. Professor, Department of General Surgery, Himalayan Institute of Medical Sciences, Dehradun, India

Description

Abstract
Aim: The aim of the present study was to identify whether preoperative bilirubin level can predict the severity
of the disease.
Material & Methods: The study was conducted in the Department of General Surgery, Himalayan Institute of
Medical Sciences, Dehradun, India for Eight months on 100 consecutive patients who were clinically diagnosed
as acute appendicitis. These patients were evaluated with Alvarado score. In addition, preoperative bilirubin
level and liver enzymes were estimated. Ultrasound abdomen was done preoperatively routinely. After surgery
histopathology was studied. The parameters which showed statistically significant results for predicting
complications were analyzed.
Results: In the conducted investigation, the gender distribution revealed that 62 individuals (62%) identified as
men, whereas 38 individuals (38%) identified as girls. Among the total of 100 instances, 45 were deemed to be
complex in nature. Out of a total of 100 patients, 60 exhibited high levels of bilirubin whereas the other 40
instances had normal bilirubin levels. Among a sample size of 100 cases, it was observed that 40 patients had a
total leucocyte count above 11000.
Conclusion: Patients diagnosed with appendicitis who have increased levels of bilirubin are at a heightened risk
for experiencing complications such as perforation, gangrene, and suppuration.

Abstract (English)

Abstract
Aim: The aim of the present study was to identify whether preoperative bilirubin level can predict the severity
of the disease.
Material & Methods: The study was conducted in the Department of General Surgery, Himalayan Institute of
Medical Sciences, Dehradun, India for Eight months on 100 consecutive patients who were clinically diagnosed
as acute appendicitis. These patients were evaluated with Alvarado score. In addition, preoperative bilirubin
level and liver enzymes were estimated. Ultrasound abdomen was done preoperatively routinely. After surgery
histopathology was studied. The parameters which showed statistically significant results for predicting
complications were analyzed.
Results: In the conducted investigation, the gender distribution revealed that 62 individuals (62%) identified as
men, whereas 38 individuals (38%) identified as girls. Among the total of 100 instances, 45 were deemed to be
complex in nature. Out of a total of 100 patients, 60 exhibited high levels of bilirubin whereas the other 40
instances had normal bilirubin levels. Among a sample size of 100 cases, it was observed that 40 patients had a
total leucocyte count above 11000.
Conclusion: Patients diagnosed with appendicitis who have increased levels of bilirubin are at a heightened risk
for experiencing complications such as perforation, gangrene, and suppuration.

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Additional details

Dates

Accepted
2023-08-15