RADIOTHERAPY 3D ISODOSEZONES GRAPHICAL OPTIMIZATION FOR HYPERFRACTIONATED TREATMENT PLANNING DOSIMETRY IN LUNG AND HEAD-NECK TUMORS WITH BIOLOGICAL EFFECTIVE DOSE MODEL

In recent lung and prostate cancer-radiotherapy contributions, [101-5], 3D imaging-processing Isodosezones [ Casesnoves, 2022 ], delimited by 3D Isodoselines were explained in lung cancer and other tumor types, such as prostate or lung. The radiotherapy model applied was the classical BED one algorithm. Modern biological-model-based Treatment Planning Optimization can get objective improvements by using Isodosezones/lines when selecting the optimal dose delivery/schedule for any personalized treatment. Improved programming, from  [ Casesnoves, May 7^th, 2024 ], and engineered software is perfectioned-developed for numerical hyperfractionated 3D TPO lung and head-neck cancer imaging-processing with upgraded previous database. Mathematical algorithms are explained-detailed. Developed programming patters and arrays are briefed. A series of imaging-processing graphics results obtained with the 3D Isodosezones Pareto-Multiobjective Optimization programming database are shown and explained in detailed. Applications in radiotherapy-oncology medical physics are subsequently briefed.