Allicin as Dermal Antibiotic against Microbial Infections

The present study aims to assess the antibacterial potential of allicin against 04 Gram-positive bacterial strains viz. Staphylococcus saprophyticus, Staphylococcus epidermis, Staphylococcus aureus, Streptococcus pyogenes and 04 Gram-negative stains-Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, Neisseria meningitis, using the Disc Diffusion Method at three concentration; 100, 200 and 300µg/ml respectively in order to treat dermal infections. The results depicted significant antibacterial activity of allicin against both the Gram-positive and Gram-negative bacterial strains. The highest antibacterial activity was noted against Neisseria meningitis at 300µg/ml (87 ± 3.5%) and the lowest activity was observed against Proteus vulgaris at 300µg/ml (33 ± 2.9%). The Minimum Inhibitory Concentration (MIC) vacillated between 100µg/ml and 200µg/ml depending on the type of microorganism. The results indicated allicin to be an extremely promising herbal medicine for the treatment of dermal infections caused by pathogenic bacterial strains.