A Prospective Observational Study to Evaluate the Maternal and Fetal Factors Associated with Intrauterine Fetal Death
- 1. Senior Resident, Department of Obstetrics and Gynecology, Patna Medical College and Hospital, Patna, Bihar, India
- 2. Professor and Head of Department, Patna Medical College and Hospital, Patna, Bihar, India
- 3. Assistant Professor, Patna Medical College and Hospital, Patna, Bihar, India
Description
Aim: To Study the maternal and fetal factors associated with intrauterine fetal death. Methods: A prospective observational study was conducted in the Department of Obstetrics and Gynecology, Patna Medical College and Hospital, Patna, Bihar, India, from July 2020 to June 2021. The cases of intra-uterine fetal death either with ultrasound reports proving IUFD or diagnosed on clinical examination by absence of fetal heart rate and fetal movements were studied. All 100 cases of IUFD with gestational age >20 weeks and <42 weeks period of gestation. Detailed obstetric history, details about present complaints and duration of present pregnancy, past obstetric performances and outcomes (including previous abortions, previous IUFD, associated toxemias, etc.,) were studied. Result: In the present study mean maternal age was 26.03 years (Mean±SD: 27.03±4.62). Out of 100 women, 2% were <20 years, 80% were 20-30 years, 16% were 30-40 years and 2% were >40 years of age. In present study, out of 100 fetuses, 53% were female and 47% were male foetuses. Weight of the foetuses were as follows: 48(48%) weighed <1000 grams, 20 (20%) weighed 1001-1500 grams, 10 (10%) weighed 1501-2000 grams, 10(10%) foetuses weighed 2001-2500 grams, 10(10%) were 2501-3000 grams and 2 (2%) weighed > 3000 grams. Mean weight of the fetus in present study was 1334 gms (Mean±SD: 1334.59±814.36). In present study, 20 (20%) IUFD were unexplained, 10 (10%) IUFD were due to abruption placentae, 5 (5%) were due to cord accidents, 16 (16%) were due to Hypertension related complications, 5 (5%) were due to diabetes, 8 (8%) were due to severe oligohydramnios, 3 (3%) were due to premature rupture of the membranes, 5 (5%) were due to Rh isoimmunisation, 22 (22%) were having major congenital anomalies, 3 (3%) were having nonimmune hydrops and 2 (2%) was due to polyhydramnios. In present study, 16(57.14%) of women had hypertension related complications. 5 (17.86%) were diabetics.5(17.86%) had Rh isoimmunisation, 1 (3.57%) had bicornuate uterus and 1 (3.57%) had septate uterus. Conclusion: PIH (hypertensive disorders of pregnancy) abruption placenta and congenital anamolies were the leading causes of the IUFD. Significant proportion of IUFD due to PIH and abruption placenta is preventable by regular ante natal care and timely intervention and treatment for PIH.
Abstract (English)
Aim: To Study the maternal and fetal factors associated with intrauterine fetal death. Methods: A prospective observational study was conducted in the Department of Obstetrics and Gynecology, Patna Medical College and Hospital, Patna, Bihar, India, from July 2020 to June 2021. The cases of intra-uterine fetal death either with ultrasound reports proving IUFD or diagnosed on clinical examination by absence of fetal heart rate and fetal movements were studied. All 100 cases of IUFD with gestational age >20 weeks and <42 weeks period of gestation. Detailed obstetric history, details about present complaints and duration of present pregnancy, past obstetric performances and outcomes (including previous abortions, previous IUFD, associated toxemias, etc.,) were studied. Result: In the present study mean maternal age was 26.03 years (Mean±SD: 27.03±4.62). Out of 100 women, 2% were <20 years, 80% were 20-30 years, 16% were 30-40 years and 2% were >40 years of age. In present study, out of 100 fetuses, 53% were female and 47% were male foetuses. Weight of the foetuses were as follows: 48(48%) weighed <1000 grams, 20 (20%) weighed 1001-1500 grams, 10 (10%) weighed 1501-2000 grams, 10(10%) foetuses weighed 2001-2500 grams, 10(10%) were 2501-3000 grams and 2 (2%) weighed > 3000 grams. Mean weight of the fetus in present study was 1334 gms (Mean±SD: 1334.59±814.36). In present study, 20 (20%) IUFD were unexplained, 10 (10%) IUFD were due to abruption placentae, 5 (5%) were due to cord accidents, 16 (16%) were due to Hypertension related complications, 5 (5%) were due to diabetes, 8 (8%) were due to severe oligohydramnios, 3 (3%) were due to premature rupture of the membranes, 5 (5%) were due to Rh isoimmunisation, 22 (22%) were having major congenital anomalies, 3 (3%) were having nonimmune hydrops and 2 (2%) was due to polyhydramnios. In present study, 16(57.14%) of women had hypertension related complications. 5 (17.86%) were diabetics.5(17.86%) had Rh isoimmunisation, 1 (3.57%) had bicornuate uterus and 1 (3.57%) had septate uterus. Conclusion: PIH (hypertensive disorders of pregnancy) abruption placenta and congenital anamolies were the leading causes of the IUFD. Significant proportion of IUFD due to PIH and abruption placenta is preventable by regular ante natal care and timely intervention and treatment for PIH.
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Additional details
Dates
- Accepted
-
2021-12-22
Software
References
- 1. Martin JA, Hoyert DL. The national fetal death file. Semin Perinatol. 2002 Feb;26(1):3-11. 2. McClure EM, Saleem S, Pasha O, Goldenberg RL. Stillbirth in developing countries: a review of causes, risk factors and prevention strategies. J Matern Fetal Neonatal Med. 2009 Mar;22(3):183-90. 3. Quibel T, Bultez T, Nizard J, Subtil. Morts foetales in utéro. Journal de gynécologie obstétrique et biologie de la reproduction. 2014;43:883-907. 4. AliyuMh, Salihu HM, Keith Lg, Ehiri JE. Extrem parity and the risk of stillbirth. Obstet Gynecol. 2005;106:446-53. 5. Andriamandimbison Z, Randriambololona DMA, Rasoanandrianina BS. Étiologies de la mort foetale in utero: à propos de 225 cas à l'hôpital de Befelatanana Madagascar: Médecine et Sante´ Tropicale. 2013;23:78-82. 6. Safarzadeh A, Ghaedniajahromi M, Ghaedniajahromi M, Rigi F, Massori N. Intra uterine fetal death and some related factors: A silent tragedy in South- eastern Iran. J Pain Relief. 2014;3:1. 7. Chippa S, Reddy VSPK, Bhavani N, Mukhopadhyay B, Giri A, Sathineedi A. Study of intrauterine fetal death. Int J Recent Trends Sci Technol. 2014Oct;12(3):624-6. 8. Rathava YR, Mehta LR, Purohit P, Narola DR, Munshi SP, Patel RV. Intra uterine fetal death: an observational study. Int J Scient Res. 2013 Nov; 2(11):388-90. 9. Nayak SR, Garg N. Determination of antepartum fetal death. J Obstet Gynecol India. 2010 Dec;60(6):494-7. 10. Choudhary A, Gupta V. Epidemology of intrauterine fetal deaths: A study in tertiary referral centre in Uttarakand. IOSR JDMS. 2014 Mar;13(3 II):03-06. 11. Shahgufta S, Shanaz A. Causes of Intrauterine foetal death. J Postgraduate Med Ins. 2006,20(3):239-242. 12. Patel S, Thaker R, Shah P, Majumder S. Study of cause and complications of IUFD. Int J Reprod Contracept Obstet Gynecol. 2014 Dec;3(4):931-5. 13. Fretts RC. Etiology and prevention of stillbirth. Am J Obstet Gynecol. 2005;193:1923-35.