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Published May 16, 2018 | Version v1
Dataset Open

Differential static light scattering (DSLS) of full-length huntingtin samples of different polyQ lengths (Q19, Q23, Q42 and Q54) – 2018/05/09

  • 1. Structural Genomics Consortium, University of Toronto

Description

Project - Huntingtin structure-function open lab notebook. 

Experiment - Differential static light scattering (DSLS) of full-length huntingtin samples of different polyQ lengths (Q19, Q23, Q42 and Q54) – 2018/05/09. To investigate how increased polyQ length of the huntingtin protein affects its biophysical properties. 

 

Notes

Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.

Files

Differential static light scattering (DSLS) of full-length huntingtin samples of different polyQ lengths (Q19, Q23, Q42 and Q54) - 20180509.pdf