A Study on Prevalence of the Adverse Drug Reactions and Dosage Pattern of Anti-Snake Venom
Creators
- 1. Associate Professor, Department of Pharmacology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, Telangana State
- 2. Assistant Professor, Department of Pharmacology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, Telangana State
Description
Background: Snake bite is a common, neglected and frequently devastating environmental and occupational disease, especially in rural areas of tropical developing countries. Anti-Snake venom (ASV) is the only promising lifesaving treatment for management of snake bite, till date. Adverse Drug reactions (ADR) is defined as “any noxious change which is suspected to be due to a drug, occurs at doses normally used in man, requires treatment or decrease in dose or indicates caution in the future use of the same drug”. Aims and Objectives: This study aimed to know prevalence of the Adverse Drug Reactions and dosage patterns of Anti-Snake Venom. Material and Methods: This prospective observational study was conducted in patients admitted with snake bite in Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar during February 2020 to December 2021. Results: Among all 150 victims of snake bite, prevalence of Adverse Drug Reaction was found to be 33%. Patients were administered with ASV I, ASV II and ASV III. Male were dominant over the female in this study. There was a no significant correlation between the various manufacturers and incidence of adverse reactions. Conclusion: Though the incidence of ADR is more troublesome, ASV is the only safe and effective drug in preventing morbidity. Different manufacturers did not show any significant variations in the adverse reactions.
Abstract (English)
Background: Snake bite is a common, neglected and frequently devastating environmental and occupational disease, especially in rural areas of tropical developing countries. Anti-Snake venom (ASV) is the only promising lifesaving treatment for management of snake bite, till date. Adverse Drug reactions (ADR) is defined as “any noxious change which is suspected to be due to a drug, occurs at doses normally used in man, requires treatment or decrease in dose or indicates caution in the future use of the same drug”. Aims and Objectives: This study aimed to know prevalence of the Adverse Drug Reactions and dosage patterns of Anti-Snake Venom. Material and Methods: This prospective observational study was conducted in patients admitted with snake bite in Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar during February 2020 to December 2021. Results: Among all 150 victims of snake bite, prevalence of Adverse Drug Reaction was found to be 33%. Patients were administered with ASV I, ASV II and ASV III. Male were dominant over the female in this study. There was a no significant correlation between the various manufacturers and incidence of adverse reactions. Conclusion: Though the incidence of ADR is more troublesome, ASV is the only safe and effective drug in preventing morbidity. Different manufacturers did not show any significant variations in the adverse reactions.
Files
IJTPR,Vol12,Issue4,Article18.pdf
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Additional details
Dates
- Accepted
-
2022-04-20
Software
References
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