Serial Serum Albumin Levels as A Prognostic Marker in Critically Ill Patients
Creators
- 1. Junior Resident, Department of General Medicine, JLN Medical College, Ajmer
- 2. Assistant Professor, Department of General Medicine, JLN Medical College, Ajmer
- 3. Associate Professor, Department of General Medicine, JLN Medical College, Ajmer
- 4. Unit Head and Senior Professor, Department of General Medicine, JLN Medical College, Ajmer
Description
Introduction: Albumin’s the most plentiful protein in human plasma. As an index of patients’ nutritional and metabolic status, it has been employed by a number of investigators. Aim: To estimate serum albumin concentrations in critically ill patients after they have been admitted to Intensive Care Unit and assess the role of continuous SA measurement as an independent diagnostic indicator. Methods: A cross-sectional observational study on 100 critically ill Patients admitted to ICU for at least 5 days or more at tertiary care hospital, Ajmer from September 2021 to September 2022. Patient with chronic liver or kidney disease, nephritic syndrome, protein-losing enteropathy and chronic malnutrition were excluded from study. Results: Out of 100 patients 62% were discharged (survivors) and 38% died (non-survivors). Using the logistic regression equation derived from our study, it was found that it correctly identified 83.87 % (Sensitivity) patients to survive and 78.95 % (Specificity) patients to die. Overall, it was 82% accurate (accuracy) in the prediction of the outcome of the patient. Conclusion: One major factor influencing the outcome of severely ill patients dependent on mechanical ventilation is likely to be a serial estimation of serum albumine levels.
Abstract (English)
Introduction: Albumin’s the most plentiful protein in human plasma. As an index of patients’ nutritional and metabolic status, it has been employed by a number of investigators. Aim: To estimate serum albumin concentrations in critically ill patients after they have been admitted to Intensive Care Unit and assess the role of continuous SA measurement as an independent diagnostic indicator. Methods: A cross-sectional observational study on 100 critically ill Patients admitted to ICU for at least 5 days or more at tertiary care hospital, Ajmer from September 2021 to September 2022. Patient with chronic liver or kidney disease, nephritic syndrome, protein-losing enteropathy and chronic malnutrition were excluded from study. Results: Out of 100 patients 62% were discharged (survivors) and 38% died (non-survivors). Using the logistic regression equation derived from our study, it was found that it correctly identified 83.87 % (Sensitivity) patients to survive and 78.95 % (Specificity) patients to die. Overall, it was 82% accurate (accuracy) in the prediction of the outcome of the patient. Conclusion: One major factor influencing the outcome of severely ill patients dependent on mechanical ventilation is likely to be a serial estimation of serum albumine levels.
Files
IJPCR,Vol15,Issue6,Article79.pdf
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Additional details
Dates
- Accepted
-
2023-05-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue6,Article79.pdf
- Development Status
- Active
References
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