Published October 30, 2023 | Version v1
Journal article Open

A Hospital-Based Study Assessing the Effect of Duration of Disease and Glycemic Control on Attention, Executive Function and Visual Reaction Time in Type 2 Diabetes Mellitus Patients

  • 1. Tutor, Department of Physiology, JNKTMCH, Madhepura, Bihar, India
  • 2. Tutor, Department of Forensic Medicine and Toxicology, Lord Buddha Koshi Medical College and Hospital, Saharsa, Bihar, India
  • 3. Assistant Professor, Department of Physiology, JNKTMCH, Madhepura, Bihar, India

Description

Abstract
Aim: The aim of the present study was to correlate duration of disease with attention, executive function and
visual reaction time in type 2 diabetes patients and to correlate HbA1c with attention, executive function and
visual reaction time in type 2 diabetes patients.
Methods: This is a cross-sectional study done on 50 type 2 diabetes mellitus subjects of either sex under the age
group of 40-60 years in the Department of Physiology for 12 months . The subjects who are able to understand
English were enrolled for the study. Written informed consent was taken and each subject was explained about
the whole procedure and objective of the study.
Results: The mean age and BMI of the patients were 56.04±4.46 and 25.55+1.96 respectively. There were 28
male and 22 females in the present study. Duration of disease was positively correlated (r=0.32) with score of
Digit Vigilance Test and p value statistically significant (0.012). A positive correlation (r=0.22) was also seen
with Visual Reaction time and p value statistically significant (0.042). Stroop test score also shows a positive
correlation (r=0.15) but without any statistical significance. HbA1c was positively correlated(r=0.58) with the
score of Digit Vigilance Test and p value statistically significant (0.01). A positive correlation (r=0.32) was also
seen with Visual Reaction time and p value statistically significant (0.01). Stroop test score also shows a
positive correlation (r=0.15) but without any statistical significance.
Conclusion: With increase in duration of the disease and poor glycemic control, sustained attention and
executive functions are declining. Also there is an increase in visual reaction time. Diabetes is a disease which
requires proper self-care and monitoring. The decline in cognitive functions can affect their activities like
glucose monitoring, medications or insulin injection patterns, diet and exercise timing

Abstract (English)

Abstract
Aim: The aim of the present study was to correlate duration of disease with attention, executive function and
visual reaction time in type 2 diabetes patients and to correlate HbA1c with attention, executive function and
visual reaction time in type 2 diabetes patients.
Methods: This is a cross-sectional study done on 50 type 2 diabetes mellitus subjects of either sex under the age
group of 40-60 years in the Department of Physiology for 12 months . The subjects who are able to understand
English were enrolled for the study. Written informed consent was taken and each subject was explained about
the whole procedure and objective of the study.
Results: The mean age and BMI of the patients were 56.04±4.46 and 25.55+1.96 respectively. There were 28
male and 22 females in the present study. Duration of disease was positively correlated (r=0.32) with score of
Digit Vigilance Test and p value statistically significant (0.012). A positive correlation (r=0.22) was also seen
with Visual Reaction time and p value statistically significant (0.042). Stroop test score also shows a positive
correlation (r=0.15) but without any statistical significance. HbA1c was positively correlated(r=0.58) with the
score of Digit Vigilance Test and p value statistically significant (0.01). A positive correlation (r=0.32) was also
seen with Visual Reaction time and p value statistically significant (0.01). Stroop test score also shows a
positive correlation (r=0.15) but without any statistical significance.
Conclusion: With increase in duration of the disease and poor glycemic control, sustained attention and
executive functions are declining. Also there is an increase in visual reaction time. Diabetes is a disease which
requires proper self-care and monitoring. The decline in cognitive functions can affect their activities like
glucose monitoring, medications or insulin injection patterns, diet and exercise timing

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Additional details

Dates

Accepted
2023-09-08