Published November 30, 2023 | Version v1
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A Hospital-Based Study Assessing the Efficacy of Intravenous Iron Sucrose for the Treatment of Iron Deficiency Anemia in Pregnancy

  • 1. Assistant Professor, Department of Obstetrics and Gynaecology, AIIMS, Nagpur, India
  • 2. Professor and Head, Department of Obstetrics and Gynecology, MGIMS, Sewagram, India
  • 3. Professor, Department of Obstetrics and Gynecology, MGIMS, Sewagram, India

Description

Abstract
Aim: The aim of the present study was to evaluate the efficacy of intravenous iron sucrose for the treatment of
iron deficiency anemia in pregnancy.
Methods: The present study carried out in Department of Obstetrics and Gynaecology, MGIMS, Sewagram,
India. The duration of the study was about 6 months. 50 pregnant women were enrolled for this study.
Results: The study results showed that the mean age of the pregnant women was 23.57±4.08 years, their mean
weight was 59.61±12.28 kg, their mean gestational week was 28.72±4.08, 8 (16%) of them had gestational
hypertension, 5 (10%) of them had gestational diabetes, 4 (8%) of them had hypothyroidism, 6% had asthma and
6% genitourinary infection whereas 4 (4%) of them had chronic kidney disease. The study results further showed
that both the hemoglobin (p<0.001) and ferritin levels (p<0.001) of females were significantly increased at term
after receiving intravenous iron sucrose as compared to the baseline. Furthermore, significant difference was
observed in PCV (p<0.001) and MCV as well (p<0.001).
Conclusion: This study concluded that the administration of iron sucrose intravenously is a secure and effective
choice in the management of iron deficiency anemia in pregnant women particularly for those who had inadequate
response to oral iron supplementation. Intravenous iron sucrose is well accepted along with a controllable safety
profile clinically and enhanced Hemoglobin and ferritin levels thus decreasing complications during pregnancy
due to iron deficiency anemia.

Abstract (English)

Abstract
Aim: The aim of the present study was to evaluate the efficacy of intravenous iron sucrose for the treatment of
iron deficiency anemia in pregnancy.
Methods: The present study carried out in Department of Obstetrics and Gynaecology, MGIMS, Sewagram,
India. The duration of the study was about 6 months. 50 pregnant women were enrolled for this study.
Results: The study results showed that the mean age of the pregnant women was 23.57±4.08 years, their mean
weight was 59.61±12.28 kg, their mean gestational week was 28.72±4.08, 8 (16%) of them had gestational
hypertension, 5 (10%) of them had gestational diabetes, 4 (8%) of them had hypothyroidism, 6% had asthma and
6% genitourinary infection whereas 4 (4%) of them had chronic kidney disease. The study results further showed
that both the hemoglobin (p<0.001) and ferritin levels (p<0.001) of females were significantly increased at term
after receiving intravenous iron sucrose as compared to the baseline. Furthermore, significant difference was
observed in PCV (p<0.001) and MCV as well (p<0.001).
Conclusion: This study concluded that the administration of iron sucrose intravenously is a secure and effective
choice in the management of iron deficiency anemia in pregnant women particularly for those who had inadequate
response to oral iron supplementation. Intravenous iron sucrose is well accepted along with a controllable safety
profile clinically and enhanced Hemoglobin and ferritin levels thus decreasing complications during pregnancy
due to iron deficiency anemia.

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Dates

Accepted
2023-11-29