Study of Effect of Zinc on the Diarrhea among Breast Feeding Babies of Maharashtra: A Study from Central India
- 1. Associate Professor, Department of Paediatrics, Krishna Mohan Medical College and Hospital, Pali Dungra, Sonkh Road, Mathura
Description
Background: Zinc deficiency can have a significant impact on general immune function, increasing susceptibility to diarrhea-causing organisms such as parasites, bacteria, and viruses. Aims & objectives: To investigate the effects of zinc on diarrhoea in Maharashtra’s breast-fed babies. Method: 180 diarrhea-affected breast-feeding babies aged 6 months to 2 years were studied and compared to 180 control breast-feeding babies of the same age. The babies were given a zinc supplement in the form of an oral syrup containing 10 mg of zinc per day (2.5 ml once daily), while the control group was given a placebo. Three follow-ups (at 6, 9, and 12 months) were completed, and the results from each follow-up were compared in both groups. Results: The interventional group had 176 (3.8) total episodes between 6 and 9 months, while the control group had 130 (4.8). Similar to the comparison between 9-12 months between two groups, the t test was 36.7 and the p value was very significant. The intervention group’s mean value was 172 (3.4), while the control group’s was 122 (4.5), with a t test of 42.05 and a p0.000 value. Conclusion: Zinc is also important for the maintenance of gut mucosal cells, according to this study. Zinc supplementation dramatically lowers the morbidity associated with diarrhea in breast-fed neonates by blocking baso-lateral potassium (k+) channels, inhibiting CAMP, inducing chloride-dependent fluid production, and maintaining mineral normality in the body.
Abstract (English)
Background: Zinc deficiency can have a significant impact on general immune function, increasing susceptibility to diarrhea-causing organisms such as parasites, bacteria, and viruses. Aims & objectives: To investigate the effects of zinc on diarrhoea in Maharashtra’s breast-fed babies. Method: 180 diarrhea-affected breast-feeding babies aged 6 months to 2 years were studied and compared to 180 control breast-feeding babies of the same age. The babies were given a zinc supplement in the form of an oral syrup containing 10 mg of zinc per day (2.5 ml once daily), while the control group was given a placebo. Three follow-ups (at 6, 9, and 12 months) were completed, and the results from each follow-up were compared in both groups. Results: The interventional group had 176 (3.8) total episodes between 6 and 9 months, while the control group had 130 (4.8). Similar to the comparison between 9-12 months between two groups, the t test was 36.7 and the p value was very significant. The intervention group’s mean value was 172 (3.4), while the control group’s was 122 (4.5), with a t test of 42.05 and a p0.000 value. Conclusion: Zinc is also important for the maintenance of gut mucosal cells, according to this study. Zinc supplementation dramatically lowers the morbidity associated with diarrhea in breast-fed neonates by blocking baso-lateral potassium (k+) channels, inhibiting CAMP, inducing chloride-dependent fluid production, and maintaining mineral normality in the body.
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Additional details
Dates
- Accepted
-
2022-07-20
Software
References
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