A Study to Analyse Various Clinical Presentation, Underlying Immunocompromised Condition, Complication of Invasive Fungal Sinusitis: An Observational Study

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Abstract (English)

Abstract
Aim: The aim of the present study was to analyze various clinical presentation, underlying
immunocompromised condition, complication of invasive fungal sinusitis.
Material & Methods: Total 50 cases of both types of invasive fungal sinusitis were included in this study. The
demographic profile, clinical presentation, underlying immunocompromised status, complication, mortality and
management of all these 50 patients were analyzed.
Results: In this study of 50 cases of invasive fungal rhinosinusitis with a male preponderance 68% (n=34). In
this study, patients having Diabetes Mellitus were more susceptible to both acute and chronic variant of invasive
fungal sinusitis. In Some patients multiple underlying immunocompromised conditions were observed. The
patients presented with symptoms of nasal obstruction (n=32) 64%, purulent rhinorrhea (n=23) 46%, headache
(n=28) 56%, facial pain (n=11) 22%, and facial swelling (n=21) 42%, epistaxis (n=27) 54%, fever (n=16) 32%,
decreased vision (n=4) 8%, diplopia (n=1) 2%. The rhinology findings like mucosal necrosis, black crust or
debris, and pus in middle meatus and septum involvement were shown. Orbital cellulitis was the most common
complication of invasive fungal rhino sinusitis. 5 patients had intracranial extension. Out of 50 patients 3
patients expired due to complication of fungal invasive fungal rhino sinusitis.
Conclusion: Invasive fungal sinusitis was most commonly observed in 3rdand4thdecade of life with male
predominance. Prolonged uncontrolled diabetic mellitus was the most common underlying
immunocompromised status. Mucor was the most common isolated fungal species. Preseptal cellulitis was the
most common complication