Comparative Study of Dexamethasone and Dexmedetomidine as Adjuvants to Bupivacaine in Supraclavicular Brachial Plexus Block in Upper Limb Surgeries
- 1. Senior Resident, Department of Anaesthesia, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar
- 2. Assistant Professor and Head of Department, Department of Anaesthesia, Sri Krishna Medical College & Hospital, Muzaffarpur, Bihar
Description
Background: One of the most recommended methods for perioperative anaesthesia and analgesia during upper limb surgical procedures is the supraclavicular brachial plexus block. The inclusion of various adjuvants can lengthen the block’s lifespan. In addition to comparing pain levels and postoperative morphine use, our goal is to examine the effectiveness of dexamethasone and dexmedetomidine as an adjuvant to bupivacaine in extending the duration of supraclavicular brachial plexus block. Methods: In this prospective randomized study, we divided 90 patients who were scheduled for upper limb procedures into three groups, each of which had 30 individuals. The three groups of patients each got 25 ml of 0.5% bupivacaine. In addition to bupivacaine, patients in Group A also received 8 mg (2 ml) of Dexamethasone, 1m gkg–1 (2ml) of Dexmedetomidine, and 2 ml of normal saline in Group B and Group C, respectively. All patients received morphine by patient-controlled analgesia (PCA) following surgery, and the block characteristics, pain ratings, and overall opioid consumption were recorded. Results: In the dexamethasone group as compared to the dexmedetomidine group, we observed a considerably extended motor block (1303.93±2 33.71 min versus 888.62±57.92 min) and protracted sensory block (1619.29±235.49 vs 1084.14±207.58 min). Both the dexamethasone and dexmedetomidine groups experienced similar levels of postoperative pain and morphine intake. Conclusion: In comparison to dexmedetomidine, dexamethasone dramatically prolongs the time that the supraclavicular brachial plexus is blocked when used as an adjuvant to bupivacaine. The two adjuvants mentioned above are both successful in reducing postoperative morphine intake.
Abstract (English)
Background: One of the most recommended methods for perioperative anaesthesia and analgesia during upper limb surgical procedures is the supraclavicular brachial plexus block. The inclusion of various adjuvants can lengthen the block’s lifespan. In addition to comparing pain levels and postoperative morphine use, our goal is to examine the effectiveness of dexamethasone and dexmedetomidine as an adjuvant to bupivacaine in extending the duration of supraclavicular brachial plexus block. Methods: In this prospective randomized study, we divided 90 patients who were scheduled for upper limb procedures into three groups, each of which had 30 individuals. The three groups of patients each got 25 ml of 0.5% bupivacaine. In addition to bupivacaine, patients in Group A also received 8 mg (2 ml) of Dexamethasone, 1m gkg–1 (2ml) of Dexmedetomidine, and 2 ml of normal saline in Group B and Group C, respectively. All patients received morphine by patient-controlled analgesia (PCA) following surgery, and the block characteristics, pain ratings, and overall opioid consumption were recorded. Results: In the dexamethasone group as compared to the dexmedetomidine group, we observed a considerably extended motor block (1303.93±2 33.71 min versus 888.62±57.92 min) and protracted sensory block (1619.29±235.49 vs 1084.14±207.58 min). Both the dexamethasone and dexmedetomidine groups experienced similar levels of postoperative pain and morphine intake. Conclusion: In comparison to dexmedetomidine, dexamethasone dramatically prolongs the time that the supraclavicular brachial plexus is blocked when used as an adjuvant to bupivacaine. The two adjuvants mentioned above are both successful in reducing postoperative morphine intake.
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IJPCR,Vol15,Issue8,Article288.pdf
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Additional details
Dates
- Accepted
-
2023-08-19
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue8,Article288.pdf
- Development Status
- Active
References
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