Published June 6, 2024 | Version v1
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Raw data for the manuscript AFM chromosomes

  • 1. ROR icon Vrije Universiteit Amsterdam

Description

  • Probed_chromosomes.zip: a zip file that contains all the raw data (and their processed version, using Bruker-JPK software) from the microrheology experiments. This folder (and all thesubfolders within it) needs to be copied inside the directory "AFM Rheology Data" of the github repository where all the other scripts are stored, in case it is missing (more information in the README file of the Github repository).
  • Images_AcrossChromatids_ChromosomeWidth_calculation.zipa zip file containing the raw AFM image files of the chromosomes probed by AFM-FS (Figure 4). The folder contains also the .gwy version of the images, i.e., their processed version using Gwyddion software and the extracted width profiles, which have been used to extract the width values within the excel file. 
  • YM_AcrossChromatidsDataset.csv: the .csv file containing the data used to create the Young's Modulus vs Height plot in the manuscript. This plot shows how the Young's modulus of different chromosomes scales with the chromosome height.
  • Fig1_Chromosome_RawImages.zip: a zip file containing the raw AFM images and their processed versions (using Gwyddion) used for the pictures in Figure 1 of the manuscript.

Files

Fig1_Chromosome_RawImages.zip

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Additional details

Funding

European Commission
MONOCHROME - Disentangling metaphase chromosome organisation one chromosome at a time 883240
European Commission
Learn4DChromosome - Learning the dynamic statistical folding of bacterial chromosomes 101122863