Evaluation of Relationship between Placental Morphology and Adverse Perinatal Outcome in Different Conditions Affecting Pregnancy
Authors/Creators
- 1. Senior Resident, Department of Obstetrics and Gynaecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
- 2. Tutor, Department of Anatomy, All India Institute of Medical Sciences, Patna, Bihar
- 3. Professor and Head of Department, Department of Obstetrics and Gynaecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar
Description
Background: The placenta serves as a mirror reflecting the fetus’s intrauterine condition. The placenta is thought to be a major contributor to neonatal and maternal mortality as well as a significant influence influencing fetal growth, which is typically linked to placental insufficiency. The placenta reflects pregnancy issues both macroscopically and microscopically, such as hypertension or gestational diabetes. Methods: Four kinds of placentas were used in the study: normal, pregnancy-induced hypertension, anemia, and diabetes mellitus. A total of 129 placentas were examined. Placental weight, placental surface area, fetal birth weight, placental coefficient, feto-placental weight ratio, and the result of the foetus, stillbirth or alive were among the many factors that were examined. Results: It was noted that the PIH group’s placental weight was noticeably lower than average. On the other hand, it was higher in the group with diabetes and anemia. The birth weight of the newborns in the PIH and anemia groups is significantly lower than that of the diabetes group. A stillbirth was noted in 3.33% of the de-liveries in the usual group. Pregnancy complications are associated with a somewhat increased percentage of stillbirths. Conclusion: The perinatal outcome is also impacted by these diseases. Along with fetal characteristics like foe-tal weight, placental properties are also changed. Therefore, diagnosing these risk factors in pregnancies during the antenatal stage will enhance the result.
Abstract (English)
Background: The placenta serves as a mirror reflecting the fetus’s intrauterine condition. The placenta is thought to be a major contributor to neonatal and maternal mortality as well as a significant influence influencing fetal growth, which is typically linked to placental insufficiency. The placenta reflects pregnancy issues both macroscopically and microscopically, such as hypertension or gestational diabetes. Methods: Four kinds of placentas were used in the study: normal, pregnancy-induced hypertension, anemia, and diabetes mellitus. A total of 129 placentas were examined. Placental weight, placental surface area, fetal birth weight, placental coefficient, feto-placental weight ratio, and the result of the foetus, stillbirth or alive were among the many factors that were examined. Results: It was noted that the PIH group’s placental weight was noticeably lower than average. On the other hand, it was higher in the group with diabetes and anemia. The birth weight of the newborns in the PIH and anemia groups is significantly lower than that of the diabetes group. A stillbirth was noted in 3.33% of the de-liveries in the usual group. Pregnancy complications are associated with a somewhat increased percentage of stillbirths. Conclusion: The perinatal outcome is also impacted by these diseases. Along with fetal characteristics like foe-tal weight, placental properties are also changed. Therefore, diagnosing these risk factors in pregnancies during the antenatal stage will enhance the result.
Files
IJPCR,Vol16,Issue5,Article90.pdf
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Additional details
Dates
- Accepted
-
2024-04-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue5,Article90.pdf
- Development Status
- Active
References
- 1. Anjankar V, et al. Placental Morphometry in Toxaemia of Pregnancy. Scholars Journal of Applied Medical Sciences. 2014; 2(1B):205-8. 2. Roberts JM and Cooper DW. Preeclampsia trio. Pathogenesis and genetics of preeclampsia. The Lancet. 2001; 357:53-6. 3. Sengupta K. Shamim A, Khandekar AR and Mahamuda B. Morphological changes of placenta in preeclampsia. Bangladesh Journal of Anatomy. 2009; 7(1):49-54. 4. Londhe PS and Mane AB. Morphometric study of placenta and its correlation in normal and hypertensive pregnancies. International Jr of Pharma and Biosciences. 2011; 2(4): B-429- 36. 5. Goswami P, Memon S and Pardeep K. Morphological, histological and radiological study of calcified placenta and its relation with foetal outcome. IOSR Journal of dental and medical sciences. 2013; 7(6):82-8. 6. Pankaj Saini, Jai Prakash Pankaj, Anjali Jain and Gyan Chand Agarwal. Effect of gestational diabetes mellitus on gross morphology of placenta: a comparative study. Int J Anat Res 2015; 3(1):889-94. 7. Saha S, Biswas S, Mitra D, Adhikari A and Saha C. Histologic and morphometric study of human placenta in gestational diabetesmellitus. Ital J Anat Embryol. 2014; 119(1):1-9. 8. Ashfaq M, Janjua MZ and Channa MA. Effect of gestational diabetes and maternal hypertension on gross morphology of placenta. J Ayub Med Coll Abbottabad. 2005; 17(1):44-4. 9. Queenan JT. Management of high risk pregnancy. 4th ed. England: Blackwell science; 1999; 261-70. 10. Majumdar S, Dasgupta H, Bhattacharya K and Bhattacharya A. A study of placenta in normal and hypertensive pregnancies. J Anat Soc India, 2005; 54(2): 34-8. 11. Udainia A and Jain ML; Morphological study of placenta in pregnancy induced hypertension with its clinical relevance. J Anat Soc India, 2001; 50(1): 24-27. 12. Thomson AM, Billewicz WZ and Hytten FE. The weight of the placenta in relation to birth weight. J Obst and Gyaecol Br Commonwealth. 1969; 76(10):865-72.13. Saigal S and Shrivastava JR. Foeto-pacental weight relationship in normal pregnancy and pre-eclampsia-eclampsia- acomparative study. Indian paediatrics. 1970; 7(2); 68-77. 14. Gunapriya Raghunath, Vijayalakshmi and Varsha Shenoy. A study on morphology and morphometry of human placenta and its clinical relevance in a population in Tamilnadu. JCDR. 2011.5(2):282-6. 15. Rath G, Garg K and Sood M. Insertion of umbilical cord on the placenta in hypertensive mother. J Anat Soc India. 2000; 49(2):149-52.