Age Related Changes in the Fibromuscular Stroma of Human Prostate Gland: An Observational Study
Creators
- 1. Assistant Professor, Department of Anatomy, Govt TD Medical College, Alappuzha
- 2. Professor, Department of Anatomy, Azeezia Medical College, Azeezia Institute of Medical Sciences
- 3. Professor, Department of Anatomy, Travancore Medical College, Kollam
- 4. Associate Professor, Department of Anatomy, Govt TD Medical College, Alappuzha
Description
Background: The prostate is the accessory gland of male reproductive system. The primary function of prostate gland is to secrete a clear, slightly alkaline fluid that contributes to the formation of seminal fluid. With advancing age, the gland undergoes significant changes both microscopic and macroscopic. The aim of this study is to demonstrate the normal changes occurring in the fibromuscular stroma of human prostate glands in various age groups. Method: An observational study on age related changes in fibromuscular stroma of human prostate gland was conducted in the Department of Anatomy, Government T D Medical College, Alappuzha. 100 specimens of human prostate glands were obtained from the Department of Forensic medicine and Department of Pathology, Government T D Medical College, Alappuzha. The pattern of changes in fibromuscular stroma in different age groups was studied using Haematoxylin, Eosin and other special stains.Results: The fibromuscular stroma was predominant in pre-pubertal prostate specimens. In post pubertal and adult p rostate specimens, there was a relative reduction in the amount of stroma. In 61-75 years age group, there was an increase in the proportion of fibromuscular stroma compared to glandular tissue in 60% of specimens. Conclusions: The present study shows that significant changes occur in the fibromuscular stroma of prostate glands beginning from birth to old age. The results of this study may be helpful in histopathological correlation of various diseases of prostate gland.
Abstract (English)
Background: The prostate is the accessory gland of male reproductive system. The primary function of prostate gland is to secrete a clear, slightly alkaline fluid that contributes to the formation of seminal fluid. With advancing age, the gland undergoes significant changes both microscopic and macroscopic. The aim of this study is to demonstrate the normal changes occurring in the fibromuscular stroma of human prostate glands in various age groups. Method: An observational study on age related changes in fibromuscular stroma of human prostate gland was conducted in the Department of Anatomy, Government T D Medical College, Alappuzha. 100 specimens of human prostate glands were obtained from the Department of Forensic medicine and Department of Pathology, Government T D Medical College, Alappuzha. The pattern of changes in fibromuscular stroma in different age groups was studied using Haematoxylin, Eosin and other special stains.Results: The fibromuscular stroma was predominant in pre-pubertal prostate specimens. In post pubertal and adult p rostate specimens, there was a relative reduction in the amount of stroma. In 61-75 years age group, there was an increase in the proportion of fibromuscular stroma compared to glandular tissue in 60% of specimens. Conclusions: The present study shows that significant changes occur in the fibromuscular stroma of prostate glands beginning from birth to old age. The results of this study may be helpful in histopathological correlation of various diseases of prostate gland.
Files
IJPCR,Vol16,Issue5,Article68.pdf
Files
(14.8 MB)
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Additional details
Dates
- Accepted
-
2024-04-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue5,Article68.pdf
- Development Status
- Active
References
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