A Hospital-Based Retrospective Observational Study Assessing Patterns of Dyslipidemia and Management Strategy in Newly Diagnosed Patients of Type 2 Diabetes Mellitus

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Abstract (English)

Aim: The aim of the present study was to evaluate the patterns of dyslipidaemia in newly diagnosed type 2 diabetes mellitus (T2DM) patients and to understand the initial management options utilised by the treating physician. Material & Methods: This retrospective observational study observed patterns of dyslipidemia and management strategy in newly diagnosed Patients of type 2 diabetes mellitus-2 (REMAP-2) study was conducted at department of General Medicine in between the duration of 1 year. Clinicians at the respective center captured the data in REMAP-2 study data capture form. Dyslipidemia was considered as: total cholesterol >200 mg/dl, low density lipoprotein cholesterol (LDL-C) >100 mg/dl, high density lipoprotein cholesterol (HDL-C) <40 mg/dl, or triglyceride >150 mg/dl. Results: The patients had a mean age of 54.6±10.32 years, and majority of the patients were males (65%) while females constituted 35% of the study population. More than half of the patients were either overweight (40%, n=4000) or obese (18.6%, n=1860). The triglyceride levels were found to be high (>150 mg/dl) in 85% (n=8190) of patients. Approximately one fourth (26.90%) of newly diagnosed T2DM patients were found to be smokers in this study. Around 52.30 percentages patients had positive family history of diabetes. Most of the patients were not very physically active or lightly active. In the context of dietary pattern, majority (60%) of the patients were non- vegetarian. Hypertension (71.10%) was the most common comorbidity followed by coronary artery disease (23.50%) in patients of newly diagnosed T2DM with dyslipidemia. Statin therapy was used in 94.80% (n=9480) patients, of which atorvastatin was the most (77.74%) preferred statin therapy. Conclusion: This study on newly diagnosed T2DM patients with dyslipidemia found that majority of the patients had hypertriglyceridemia, family history of diabetes and was physically inactive. More than half of T2DM patients were either overweight or obese. More than 2/3rd of the patients had mixed dyslipidemia. Statins were prescribed to the majority of these patients and atorvastatin was the most commonly prescribed statin in Indian T2DM. patients with dyslipidemia