A Hospital-Based Survey of Distribution of Hepatitis a in Clinically Suspected Cases of Acute Viral Hepatitis: An Observational Study
Creators
- 1. 1 Tutor, Department of Microbiology, Patna Medical College and Hospital, Patna, Bihar, India
- 2. 3 Tutor, Department of Microbiology, Patna Medical College and Hospital, Patna, Bihar, India
- 3. Professor and HOD, Department of Microbiology, Patna Medical College and Hospital, Patna, Bihar, India
Description
Aim: The aim of the present study was to assess the seroprevalence of Hepatitis A cases and profile of clinically
suspected cases of acute viral hepatitis at a tertiary hospital.
Methods: The present study was prospective and observational study conducted in the Department of
Microbiology, PMCH, Patna, Bihar, India for the period of one year. In present study, serum of 200 cases of
suspected hepatitis was tested.
Results: Suspected hepatitis cases were most commonly observed in 15 – 30 years of age group (45%) followed
by 31 to 45 years of age group (30%) and less than 15 years (18%). Suspected hepatitis cases were most
commonly observed in female (53%) population as compared to male (47%). The most common clinical
features amongst cases of hepatitis was fever (98%) followed by malaise (97%), abdominal pain (88%), Yellow
discoloration of urine (24%) and loss of appetite (14%). Anti HAV test (IgM) was reactive most commonly in
less than 15 years of age group followed by 15 to 30 years and 31-45 years. Amongst HAV positive cases there
was slightly higher number of female cases as compared to male cases. Mean Total Bilirubin, SGOT/AST,
SGPT, ALP and A/G ratio amongst hepatitis A cases was 2.86± 2.46, 113 ± 28.73, 308 ± 152, 1365 ± 596 and
0.68 ± 0.24 respectively.
Conclusion: HAV infections are prevalent infections among clinically suspected acute viral hepatitis patients
and remain a major health problem in developing countries. Reduced incidence of HAV infection in respective
age group indicates the role of improved sanitary measures and public education.
Abstract (English)
Aim: The aim of the present study was to assess the seroprevalence of Hepatitis A cases and profile of clinically
suspected cases of acute viral hepatitis at a tertiary hospital.
Methods: The present study was prospective and observational study conducted in the Department of
Microbiology, PMCH, Patna, Bihar, India for the period of one year. In present study, serum of 200 cases of
suspected hepatitis was tested.
Results: Suspected hepatitis cases were most commonly observed in 15 – 30 years of age group (45%) followed
by 31 to 45 years of age group (30%) and less than 15 years (18%). Suspected hepatitis cases were most
commonly observed in female (53%) population as compared to male (47%). The most common clinical
features amongst cases of hepatitis was fever (98%) followed by malaise (97%), abdominal pain (88%), Yellow
discoloration of urine (24%) and loss of appetite (14%). Anti HAV test (IgM) was reactive most commonly in
less than 15 years of age group followed by 15 to 30 years and 31-45 years. Amongst HAV positive cases there
was slightly higher number of female cases as compared to male cases. Mean Total Bilirubin, SGOT/AST,
SGPT, ALP and A/G ratio amongst hepatitis A cases was 2.86± 2.46, 113 ± 28.73, 308 ± 152, 1365 ± 596 and
0.68 ± 0.24 respectively.
Conclusion: HAV infections are prevalent infections among clinically suspected acute viral hepatitis patients
and remain a major health problem in developing countries. Reduced incidence of HAV infection in respective
age group indicates the role of improved sanitary measures and public education.
Files
IJCPR,Vol16,Issue2,Article39.pdf
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Additional details
Dates
- Accepted
-
2024-02-18