A Comparative Study of Widal Test and Typhidot Test in the Diagnosis of Typhoid Fever in A Tertiary Care Hospital in Western U.P.
Creators
- 1. Assistant Professor, Paediatrics, G S Medical College and Hospital
- 2. Assistant Professor, Microbiology, G S Medical College and Hospital
- 3. Associate Professor, Community Medicine, G S Medical College and Hospital
- 4. Associate Professor, Pathology, G S Medical College and Hospital
- 5. Associate Consultant, Gastroenterology, Akaash Healthcare, Dwarka
Description
Background: Enteric fever (Typhoid fever) is a common systemic infectious disease worldwide, especially in developing countries like India and continues to be one of the leading causes of morbidity and mortality. It is caused by the bacterium Salmonella typhi or Salmonella paratyphi serotypes A, B and C. The clinical diagnosis of Enteric fever traditionally depends on Blood culture and Widal tests. However limitations such as longer time for Blood culture results and difficulties in the interpretation of Widal tests make them unpractical for screening patients in endemic regions and lead to misdiagnosis and missed diagnosis. Aims and Objectives: In this study we compare the sensitivity and specificity of Widal test and Typhidot test, in the diagnosis of Typhoid fever. Material and Methods: The comparison for the presence of the Salmonella antibodies done by the Typhidot and Widal tube agglutination test in central lab of gs medical college over a period of jan23 to jun23. Results: Out of 350 blood specimen, 42.8% cases were positive by Typhidot test and 31.42% cases were positive by Widaltest. Conclusion: Typhidot is a rapid and more sensitive test for early diagnosis of typhoid fever. It offers the advantage of early and rapid diagnosis and helps in early institution of therapy. Widal test showed the sensitivity and specificity of 53.3% &73.1% respectively. Typhidot test showed sensitivity of 80% and specificity of 63.3%.
Abstract (English)
Background: Enteric fever (Typhoid fever) is a common systemic infectious disease worldwide, especially in developing countries like India and continues to be one of the leading causes of morbidity and mortality. It is caused by the bacterium Salmonella typhi or Salmonella paratyphi serotypes A, B and C. The clinical diagnosis of Enteric fever traditionally depends on Blood culture and Widal tests. However limitations such as longer time for Blood culture results and difficulties in the interpretation of Widal tests make them unpractical for screening patients in endemic regions and lead to misdiagnosis and missed diagnosis. Aims and Objectives: In this study we compare the sensitivity and specificity of Widal test and Typhidot test, in the diagnosis of Typhoid fever. Material and Methods: The comparison for the presence of the Salmonella antibodies done by the Typhidot and Widal tube agglutination test in central lab of gs medical college over a period of jan23 to jun23. Results: Out of 350 blood specimen, 42.8% cases were positive by Typhidot test and 31.42% cases were positive by Widaltest. Conclusion: Typhidot is a rapid and more sensitive test for early diagnosis of typhoid fever. It offers the advantage of early and rapid diagnosis and helps in early institution of therapy. Widal test showed the sensitivity and specificity of 53.3% &73.1% respectively. Typhidot test showed sensitivity of 80% and specificity of 63.3%.
Files
IJPCR,Vol15,Issue11,Article226.pdf
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Additional details
Dates
- Accepted
-
2023-10-04
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue11,Article226.pdf
- Development Status
- Active
References
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