Status of Vitamin D in Polycystic Ovary Syndrome: A Case Control Study
Authors/Creators
- 1. Postgraduate Student (Final Year), Department of Biochemistry, Patna Medical College, Patna, Bihar
- 2. Professor, Department of Biochemistry, Patna Medical College, Patna, Bihar
- 3. Professor and Head of Department, Department of Biochemistry, Patna Medical College, Patna, Bihar
Description
Background: Endocrine and metabolic abnormalities are clinical manifestations of PCOS, or polycystic ovarian syndrome. The lack of vitamin D in many people worldwide, regardless of age, has led to a significant increase in interest in the nutrient in recent years. This study compared and measured the vitamin D levels of healthy women and PCOS patients. Methods: It was a case-control study. In this study, 75 PCOS patients and 75 age-matched healthy controls were enrolled. Using the ELISA technique, an immunoassay method was used to estimate the serum level of Vitamin D. When appropriate, the independent t-test and chi square test were used to compare the data. Results: Compared to healthy controls (34.12±7.41 ng/ml), PCOS patients had a significantly (p<0.0001) lower total blood vitamin D level (21.91± 8.49 ng/ml). Conclusion: The observation of hypovitaminosis D in PCOS cases suggested a potential role for vitamin D in the pathophysiological alterations associated with the illness.
Abstract (English)
Background: Endocrine and metabolic abnormalities are clinical manifestations of PCOS, or polycystic ovarian syndrome. The lack of vitamin D in many people worldwide, regardless of age, has led to a significant increase in interest in the nutrient in recent years. This study compared and measured the vitamin D levels of healthy women and PCOS patients. Methods: It was a case-control study. In this study, 75 PCOS patients and 75 age-matched healthy controls were enrolled. Using the ELISA technique, an immunoassay method was used to estimate the serum level of Vitamin D. When appropriate, the independent t-test and chi square test were used to compare the data. Results: Compared to healthy controls (34.12±7.41 ng/ml), PCOS patients had a significantly (p<0.0001) lower total blood vitamin D level (21.91± 8.49 ng/ml). Conclusion: The observation of hypovitaminosis D in PCOS cases suggested a potential role for vitamin D in the pathophysiological alterations associated with the illness.
Files
IJPCR,Vol15,Issue12,Article152.pdf
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Additional details
Dates
- Accepted
-
2023-11-30
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue12,Article152.pdf
- Development Status
- Active
References
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