Published December 30, 2023 | Version https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue12,Article37.pdf
Journal article Open

Histopathological Spectrum of Various Prostatic Lesions in TURP Specimens: A Retrospective Study

  • 1. Associate Professor, Department of General Surgery, SCB Medical College, Cuttack
  • 2. Assistant Professor, Department of General Surgery, SCB Medical College, Cuttack
  • 3. Assistant Professor, Department of General Medicine, SCB Medical College, Cuttack
  • 4. Assistant Professor, Department of Orthopaedics, Bhima Bhoi Medical College, Balangir
  • 5. Junior Resident, SVNIRTAR, Cuttack

Description

Background: In adult men, benign prostatic hyperplasia (BPH) and prostate cancer are major causes of morbidity and death. Other prostatic lesions include inflammatory conditions and lesions in situ. TURP is required to detect these abnormalities, particularly prostatic cancer. The purpose of this study was to assess the histomorphological spectrum of distinct prostatic lesions in TURP tissues. Materials and Procedures: A total of 85 TURP specimens were investigated during a two-year period, from April 2018 to March 2020. The cases were examined in terms of their entire history, clinical examination, and histological results. The diagnostic criteria were modified from World Health Organization (WHO) recommendations. Result: Over a 2-year period, 85 prostate TURP tissues were analyzed, with 81 instances of benign lesions (95.2%) and 4 cases of malignant lesions (4.8%). Among the benign lesions were 54 instances of benign prostatic hyperplasia (BPH), 24 cases of BPH with prostatitis, and 2 cases of granulomatous prostatitis. Conclusion: TURP is important in the diagnosis of prostatic abnormalities. The benign lesions outnumber the malignant ones. The modified Gleason score is used to grade prostate cancer because it is straightforward and accurate.

 

 

Abstract (English)

Background: In adult men, benign prostatic hyperplasia (BPH) and prostate cancer are major causes of morbidity and death. Other prostatic lesions include inflammatory conditions and lesions in situ. TURP is required to detect these abnormalities, particularly prostatic cancer. The purpose of this study was to assess the histomorphological spectrum of distinct prostatic lesions in TURP tissues. Materials and Procedures: A total of 85 TURP specimens were investigated during a two-year period, from April 2018 to March 2020. The cases were examined in terms of their entire history, clinical examination, and histological results. The diagnostic criteria were modified from World Health Organization (WHO) recommendations. Result: Over a 2-year period, 85 prostate TURP tissues were analyzed, with 81 instances of benign lesions (95.2%) and 4 cases of malignant lesions (4.8%). Among the benign lesions were 54 instances of benign prostatic hyperplasia (BPH), 24 cases of BPH with prostatitis, and 2 cases of granulomatous prostatitis. Conclusion: TURP is important in the diagnosis of prostatic abnormalities. The benign lesions outnumber the malignant ones. The modified Gleason score is used to grade prostate cancer because it is straightforward and accurate.

 

 

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Additional details

Dates

Accepted
2023-11-30

References

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