Published May 8, 2024 | Version v1
Software Open

Supplementary data and code for Gupta and Heinrichs et al. 2024

  • 1. University of California Los Angeles David Geffen School of Medicine
  • 2. UCLA Geffen School of Medicine

Description

Code and R data files for publication: "Investigating the basis of lineage decisions and developmental trajectories in the dorsal spinal cord through pseudotime analyses" Development, 2024.

RDS are processed data files

  • subRA.rds is just RA protocol
    • generated in object creation - individual datasets.R
  • subBMP.rds is just BMP protocol
    • generated in object creation - individual datasets.R
  • with pseudotime updated.rds is RA and BMP combined with pseudotime analysis added
    • generated in Data loading and integration.R and then monocle.R and then analyzed mainly in object analysis.R but also in other files
  • briscoe.sub.intergrated is dataset from delile et al
    • generated in briscoe analysis.R
    • integration with our dataset.R is briscoe dataset and our two datasets combined with further analysis in knn UMAP analysis.R
  • each shiny data rds file goes with its respective app.R file
    • these rds files have more genes than could be uploaded to the online shiny app

Relevant citations for code available in linked publication

Files

Files (4.1 GB)

Name Size Download all
md5:5dbee8717bad41991cd01126c4c9c8a1
6.2 kB Download
md5:e276fad987bebfe1369934687498dd4e
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md5:e3ffffb51b30d5a3d1a83e8966c6d7c8
11.2 kB Download
md5:f98ea626a1f04ea867c5d85db3b9d48b
2.1 GB Download
md5:b174d09912719f163331d94fabfe86c9
18.4 MB Download
md5:1aec43a5d48c60399a850f9827f44e8a
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md5:cb7cbe0037848e7d3d43a25acfc684d8
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md5:d784422fcd215f453552bc00802d5bba
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md5:844c6116b90f2f837be599aefe514190
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md5:a55e0c206374572c07d96ec232bfeaa7
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md5:5b8275aacb46a504ba18ac1fce5ca14f
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md5:4a5179533ec549a1959d15425b01bfc6
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md5:1a003b0a9497160836dcfa95d8cbfef7
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md5:aa4f357b0a8471ad5a4afaf1d77702a3
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md5:a5ee4adff7b6005c30efb0b07190ab94
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md5:99ba903686a2029801334e9fbe840b8e
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md5:acab6c10d7cc5e472e584748f8198b00
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md5:fce08eceddd5070c4deea87e3cb1caa8
52.4 MB Download
md5:88ab346b0db8d3bf9e16415d62a24507
5.0 kB Download
md5:e677a256ee2496fd7ad7fc74bcdcbb3b
371.4 MB Download
md5:e9c1a9d32403ba984e31583203306b28
311.2 MB Download
md5:36b555f1b6b5d3a85c73c8edb6c5235d
6.1 kB Download
md5:db3b3d7968e519a7c52a9eca415c89b4
1.2 GB Download

Additional details

Related works

Is supplement to
Publication: 10.1242/dev.202209 (DOI)

Software

Programming language
R