Published May 6, 2024 | Version v1
Software Open

iIMPACT: Integrating Image and Molecular Profiles for Spatial Transcriptomics Analysis

Authors/Creators

  • 1. Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, The University of Texas Southwestern Medical Center
  • 2. Department of Statistics and Data Science, Southern Methodist University
  • 3. Department of Statistics, The Chinese University of Hong Kong
  • 4. Department of Mathematical Sciences, The University of Texas at Dallas
  • 5. Department of Pathology, The University of Texas Southwestern Medical Center

Description

iIMPACT is a novel method which integrates image and molecular profiles for spatial transcriptomics analysis. It is a multi-stage statistical method for histology-based spatial domain identification and domain-specific differentially expressed gene detection.

This package contains the iIMPACT software and processed datasets.

Files

Codes.zip

Files (402.8 MB)

Name Size Download all
md5:95b579335364e7c91328da67e4c2ed67
4.1 MB Preview Download
md5:e2b74b2c406c7cae6e80b779c3b45c17
398.8 MB Preview Download

Additional details

Software

Repository URL
https://github.com/Xijiang1997/iIMPACT
Programming language
R , C++