Published January 30, 2024 | Version https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue1,Article152.pdf
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The Prevalence of Pathogens Causing Bacteraemia Along with Antibiotic Sensitivity Pattern in Tertiary Care Hospital

  • 1. Assistant Professor, Department of Microbiology, Radha Devi Jageshwari Memorial Medical College & Hospital, Turki, Muzaffarpur, Bihar

Description

Background: Bacteraemia is the medical term for the presence of bacteria in the blood or bloodstream. Septicaemia is defined as the growth of bacteria and the release of toxins into the bloodstream. Bacteraemia can be temporary, sporadic, or persistent. Intravascular and extravascular infections are the two types of blood stream infections. It has been demonstrated that determining the antimicrobial sensitivity pattern and performing early microbiological diagnostics increase treatment outcomes. The purpose of this research is to identify the causing agents and ascertain the pattern of antimicrobial sensitivity from blood samples taken from individuals suffering from bacteremia or sepsis. Methods: Prospective cross-sectional study carried out in a hospital setting at Turki Muzaffarpur, Bihar’s RDJMMCH. Between May 2023 and October 2023, 765 blood samples from patients with bacteremia were taken. The blood samples were drawn and handled according to protocol. The organisms were isolated and identified in accordance with accepted practices. In accordance with CLSI recommendations, antimicrobial sensitivity was established using Kirby Bauer’s Disc diffusion method. Results: Of the 765, 349 (45.62%) were female and 416 (54.37%) were male. Out of the 765 samples in total, 114 (14.9%) had good results. The results of this investigation indicated that 60 (52.66%) Gram positive organisms were more common than 51 (44.73%) and 3 (2.63%) Gram negative organisms or fungal isolates.Conclusion: Patients’ morbidity and death can be decreased with prompt detection and adequate treatment. These studies will also aid in the development of policies and guidelines regarding antibiotics to improve patient outcomes.

 

 

Abstract (English)

Background: Bacteraemia is the medical term for the presence of bacteria in the blood or bloodstream. Septicaemia is defined as the growth of bacteria and the release of toxins into the bloodstream. Bacteraemia can be temporary, sporadic, or persistent. Intravascular and extravascular infections are the two types of blood stream infections. It has been demonstrated that determining the antimicrobial sensitivity pattern and performing early microbiological diagnostics increase treatment outcomes. The purpose of this research is to identify the causing agents and ascertain the pattern of antimicrobial sensitivity from blood samples taken from individuals suffering from bacteremia or sepsis. Methods: Prospective cross-sectional study carried out in a hospital setting at Turki Muzaffarpur, Bihar’s RDJMMCH. Between May 2023 and October 2023, 765 blood samples from patients with bacteremia were taken. The blood samples were drawn and handled according to protocol. The organisms were isolated and identified in accordance with accepted practices. In accordance with CLSI recommendations, antimicrobial sensitivity was established using Kirby Bauer’s Disc diffusion method. Results: Of the 765, 349 (45.62%) were female and 416 (54.37%) were male. Out of the 765 samples in total, 114 (14.9%) had good results. The results of this investigation indicated that 60 (52.66%) Gram positive organisms were more common than 51 (44.73%) and 3 (2.63%) Gram negative organisms or fungal isolates.Conclusion: Patients’ morbidity and death can be decreased with prompt detection and adequate treatment. These studies will also aid in the development of policies and guidelines regarding antibiotics to improve patient outcomes.

 

 

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Dates

Accepted
2023-12-26

References

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