Published April 30, 2024 | Version v1
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A Comprehensive Overview on Nanoemulsion drug delivery system.

Description

This study explores the formulation and optimization of a nanoemulsion for enhanced drug delivery. Nanoemulsions are colloidal dispersions with droplet sizes in the nanometer range offering increased stability and improved bioavailability. The primary focus is on manipulating particle size through two key methods: Ultrasonication and High-pressure homogenization. These techniques are employed to achieve the desired nanoscale range enhancing the formulations efficiency. The impact of pH on nanoemulsion stability and drug release is investigated recognizing its influence on droplet surface charge and interfacial properties. Viscosity measurements are conducted to understand the formulations rheological behavior crucial for its administration and therapeutic effectiveness. The study also assessesdrug content within the nanoemulsion to ensure accurate dosing. In vitro studies are conducted to evaluate the nanoemulsions performance in simulated biological environments. These investigations include drug release kinetics permeability and overall efficacy. The results aim to provide insights intothe nanoemulsions potential as a drug delivery system shedding light on its stability, particle size optimization and impact on drug release profiles. Overall, this research contributes valuable knowledge to the field of pharmaceutical science offering a comprehensive understanding of the key parameters influencing nanoemulsion formulation and its potential applications in drug delivery.

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