Alzheimer Disease PGS Aggregated Ranked

This dataset represents a resource for Alzheimer's Disease Polygenic Scores (AD PGSs) with enhanced annotations and aggregated rankings of genetic variants. Curated and annotated PGS files are in AD_aggregated_ranks.csv

AD_aggregated_ranks.csv contains aggregtaed ranks of genetic variants based on the effect weight across mulitple PGSs.
Below are the descriptions of the columns in the AD_aggregated_ranks.csv:

hm_rsID: Reference SNP ID from dbSNP database.
hm_chr: Chromosome number where the SNP is located.
hm_pos: Position of the SNP on the chromosome.
annot.symbol: Gene symbol associated with the SNP.
annot.type: Type of genetic annotation (e.g., intronic, exonic).
weighted_means: Weighted mean of polygenic scores across different studies.
mean reciprocal rank (Dowdall): Mean reciprocal rank of SNPs, used in rank aggregation, following Dowdall's method.
RRA_score: Robust Rank Aggregation score.
Stuart_score: Score based on Stuart's method of rank aggregation.
Min_score: Minimum rank score across all aggregated studies.
Geo_score: Geometric mean score.
Mean_score: Arithmetic mean of all rank scores.
Med_score: Median of the rank scores.