Isolation and Antibiotics Resistance Pattern of Micro-Organism Recovered From Diabetic Foot Patients
Creators
- 1. Associate Professor, Department of Microbiology, Abhishek I Memorial Medical College and Research, Junwani, Bhilai, Chhattisgarh
- 2. Associate Professor, Department of Pathology, Abhishek I Memorial Medical College and Research, Junwani, Bhilai, Chhattisgarh
- 3. Professor, Department of Pharmacology, Shri Balaji Institute of Medical Sciences, Raipur, Chhattisgarh
- 4. Associate Professor, Department of Microbiology, N.S.C. Government Medical College, Khandwa, M.P
Description
Background: Diabetic foot infections (DFIs) are a major public health issue and identification of the microorganisms causing such polymicrobial infections is useful to find out appropriate antibiotic therapy. Aim: To evaluate the bacteriological profile of patients with diabetic foot ulcers and their antibiotic susceptibility pattern. Methods: A cross-sectional study was carried out in the department of microbiology. A total of 120 patients diagnosed with diabetic foot ulcer (DFU) were enrolled. The pus and tissue samples were collected accordance to proper aseptic precautions. Culture, identification of organism and their antibiotic susceptibility pattern was done by Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: This study of 120 diabetic foot ulcer patients revealed a male predominance. Most patients were in 46-60 years age group. Among gram-positive bacteria staphylococcus aureus whereas among gram negative bacteria pseudomonas and Klebsiella pneumoniae was common. Methicillin resistance Staphylococcus aureus (MRSA) was 87.2% cases. Gram positive cocci were least resistance to vancomycin and Linezolid. E.coli and Klebsiella were most resistance to Ampicillin whereas Pseudomonas was highly resistance to Cefipime and Ceftriaxone whereas least resistance to imipenem and meropenem. Conclusions: The knowledge on the antibiotic sensitivity pattern of isolates help in planning treatment with the appropriate antibiotic regimen. This, in turn, helps to prevent the emergence of drug-resistant organisms and minimizing healthcare costs.
Abstract (English)
Background: Diabetic foot infections (DFIs) are a major public health issue and identification of the microorganisms causing such polymicrobial infections is useful to find out appropriate antibiotic therapy. Aim: To evaluate the bacteriological profile of patients with diabetic foot ulcers and their antibiotic susceptibility pattern. Methods: A cross-sectional study was carried out in the department of microbiology. A total of 120 patients diagnosed with diabetic foot ulcer (DFU) were enrolled. The pus and tissue samples were collected accordance to proper aseptic precautions. Culture, identification of organism and their antibiotic susceptibility pattern was done by Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: This study of 120 diabetic foot ulcer patients revealed a male predominance. Most patients were in 46-60 years age group. Among gram-positive bacteria staphylococcus aureus whereas among gram negative bacteria pseudomonas and Klebsiella pneumoniae was common. Methicillin resistance Staphylococcus aureus (MRSA) was 87.2% cases. Gram positive cocci were least resistance to vancomycin and Linezolid. E.coli and Klebsiella were most resistance to Ampicillin whereas Pseudomonas was highly resistance to Cefipime and Ceftriaxone whereas least resistance to imipenem and meropenem. Conclusions: The knowledge on the antibiotic sensitivity pattern of isolates help in planning treatment with the appropriate antibiotic regimen. This, in turn, helps to prevent the emergence of drug-resistant organisms and minimizing healthcare costs.
Files
IJPCR,Vol16,Issue2,Article288.pdf
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Additional details
Dates
- Accepted
-
2024-02-16
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue2,Article288.pdf
- Development Status
- Active
References
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