Study to Assess Histopathology and to Classify Tumours of Prostate According to Modified Gleason Grading System: an Observational Study
- 1. Assistant Professor, Department of Pathology, Lord Buddha Koshi Medical College and Hospital, Saharsa, Bihar, India
- 2. Associate Professor, Department of Pathology, Lord Buddha Koshi Medical College and Hospital, Saharsa, Bihar, India
Description
Aim: The aim of the present study was to assess histopathology and to classify tumours of prostate as per recommendations of WHO and to analyse cases of Adenocarcinoma of prostate according to Modified Gleason grading system. Methods: An observational study conducted in the Department of Pathology for the period of 2 years and 100 patients were included in the study. Results: All prostatic specimens were broadly classified into benign 90 (90%) and malignant 9 (9%). We reported 1 (1%) case of Prostatic Intra-epithelial Neoplasia (PIN). Maximum cases of BPH 39 (39%) were seen in the 61-70 years age group. Cases of BPH with co-existing chronic prostatitis were 6 (6%) and that with acute prostatitis were 2 (2%). Less frequent findings were BPH with basal cell hyperplasia 3 (3%) and BPH with squamous metaplasia 1 (1%). We reported 10 cases of adenocarcinoma prostate with modified Gleason Grading system. The most common score obtained was Gleason’s score 7 in 3 cases out of the total 10 adenocarcinoma cases. Conclusion: Maximum number of cases of adenocarcinoma was seen in 61-70 years age group. It is necessary to study all prostate biopsies in order to identify premalignant lesions, proliferative activity and grade of inflammation. Histopathological diagnosis and grading plays a definitive role in the management of prostatic carcinoma.
Abstract (English)
Aim: The aim of the present study was to assess histopathology and to classify tumours of prostate as per recommendations of WHO and to analyse cases of Adenocarcinoma of prostate according to Modified Gleason grading system. Methods: An observational study conducted in the Department of Pathology for the period of 2 years and 100 patients were included in the study. Results: All prostatic specimens were broadly classified into benign 90 (90%) and malignant 9 (9%). We reported 1 (1%) case of Prostatic Intra-epithelial Neoplasia (PIN). Maximum cases of BPH 39 (39%) were seen in the 61-70 years age group. Cases of BPH with co-existing chronic prostatitis were 6 (6%) and that with acute prostatitis were 2 (2%). Less frequent findings were BPH with basal cell hyperplasia 3 (3%) and BPH with squamous metaplasia 1 (1%). We reported 10 cases of adenocarcinoma prostate with modified Gleason Grading system. The most common score obtained was Gleason’s score 7 in 3 cases out of the total 10 adenocarcinoma cases. Conclusion: Maximum number of cases of adenocarcinoma was seen in 61-70 years age group. It is necessary to study all prostate biopsies in order to identify premalignant lesions, proliferative activity and grade of inflammation. Histopathological diagnosis and grading plays a definitive role in the management of prostatic carcinoma.
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Additional details
Dates
- Accepted
-
2023-06-26
Software
References
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