Published April 26, 2024 | Version v1
Journal article Open

Investigation of Biological Properties of Acetone O-(4-chlorophenylsulfonyl)oxime and Acetone O-(2-naphthylsulfonyl)oxime

  • 1. Mardin Artuklu University Graduate Education Institute Department of Biology, MARDİN
  • 2. Mardin Artuklu University Vocational Higher School of Health Services Department of Medical Services and Techniques, MARDİN
  • 3. Siirt University Medical Faculty Department of Medical Biology, SİİRT

Description

The purpose of this study is to survey if acetone O-(4 chlorophenylsulfonyl) oxime (1a) and acetone O-(2-naphtylsülphonyl)oxime (2a) compounds have antimicrobial and antioxidant properties or not. For this purpose, the antioxidant activity of the compounds was tested using the DPPH free radical method and the method of determining the antibacterial activity of newly synthesized compounds. As a result, compound 1a shows better antioxidant activity than compound 2a at all tested concentrations. The antibacterial activities of sulfonate derivatives on Staphylococcus aureus, Pseudomonas aeruginosa Escherichia coli, and Enterococcus hirae strains were investigated and it was determined that all compounds showed partial antibacterial activity for S. aureus, E. coli, and K. pneumoniae strains.

Files

Article 2.pdf

Files (828.0 kB)

Name Size Download all
md5:4724984efb9bbb53734414d43fe4de0d
828.0 kB Preview Download