Published December 30, 2023 | Version http://impactfactor.org/PDF/IJTPR/13/IJTPR,Vol13,Issue12,Article60.pdf
Journal article Open

A Study Assessing Histopathological Features and Classify Tumors of Prostate as Per Recommendations of WHO: An Observational Study

Authors/Creators

  • 1. Assistant Professor, Department of Pathology, Lord Buddha Koshi Medical College and Hospital, Saharsa, Bihar, India
  • 2. Associate Professor, Department of Pathology, Shree Narayan Medical Institute and Hospital, Saharsa, Bihar, India

Description

Aim: The aim of the present study was to assess the incidence, age distribution, gross and histopathological features of lesions of prostate and to classify tumours of prostate as per recommendations of WHO. Methods: An observational study conducted in the Department of Pathology for the period of 2 years and 100 patients were included in the study. Results: Most prostatic samples were benign (90%), whereas 9% were cancerous. Our analysis found 1 case of Prostatic Intra-epithelial Neoplasia (PIN). BPH was most common in those aged 61–70, with 39 cases (39%). Six BPH patients (6%) had chronic prostatitis and two (2%) had acute prostatitis. Three BPH patients (3%) had basal cell hyperplasia and one had squamous metaplasia. We recorded 10 prostate cancer cases utilizing modified Gleason Grading. Gleason’s score 7 was the most common in 3 of 10 adenocarcinomas. Conclusion: Adenocarcinoma was most common in those aged 61–70. All prostate biopsies must be examined for premalignant abnormalities, proliferative activity, and inflammation. Successful prostate cancer therapy depends on histology detection and classification.

Abstract (English)

Aim: The aim of the present study was to assess the incidence, age distribution, gross and histopathological features of lesions of prostate and to classify tumours of prostate as per recommendations of WHO. Methods: An observational study conducted in the Department of Pathology for the period of 2 years and 100 patients were included in the study. Results: Most prostatic samples were benign (90%), whereas 9% were cancerous. Our analysis found 1 case of Prostatic Intra-epithelial Neoplasia (PIN). BPH was most common in those aged 61–70, with 39 cases (39%). Six BPH patients (6%) had chronic prostatitis and two (2%) had acute prostatitis. Three BPH patients (3%) had basal cell hyperplasia and one had squamous metaplasia. We recorded 10 prostate cancer cases utilizing modified Gleason Grading. Gleason’s score 7 was the most common in 3 of 10 adenocarcinomas. Conclusion: Adenocarcinoma was most common in those aged 61–70. All prostate biopsies must be examined for premalignant abnormalities, proliferative activity, and inflammation. Successful prostate cancer therapy depends on histology detection and classification.

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Identifiers

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http://impactfactor.org/PDF/IJTPR/13/IJTPR,Vol13,Issue12,Article60.pdf

Dates

Accepted
2023-07-23

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Repository URL
http://impactfactor.org/PDF/IJTPR/13/IJTPR,Vol13,Issue12,Article60.pdf

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