Published January 31, 2024 | Version http://impactfactor.org/PDF/IJTPR/14/IJTPR,Vol14,Issue1,Article40.pdf
Journal article Open

Determination of Prostatic Specific Antigen (PSA) Level in Patients with Polycystic Ovary Syndrome (PCOS)

  • 1. Department of Biochemistry, Post Graduate Student, Jhalawar Medical College, Jhalawar, Rajasthan
  • 2. Department of Biochemistry, Senior Professor, Jhalawar Medical College, Jhalawar, Rajasthan
  • 3. Department of Biochemistry, Professor& Head, Jhalawar Medical College, Jhalawar, Rajasthan

Description

Introduction: The polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder, clinically characterized by oligo-ovulation/chronic anovulation, menstrual irregularities and hyperandrogenism. Objectives: The aim of this study was determined and compare the concentration PSA in 50 patients with PCOS and 50 healthy female controls. Result: The present observation showed that the mean level of PSA concentration in case (group I) was found to be (0.84 ± 0.30 ng/ml) and in control (group II) was found to be (0.53 ± 0.29 ng/ml). Statistical analysis showed that p < 0.05. Conclusion: The PSA concentration in PCOS patient was found to be higher than that of healthy controls, and the difference was statistically significant. A comparatively elevated PSA level in PCOS women as compared to normal women is an indication of hyperandrogenism.

Abstract (English)

Introduction: The polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder, clinically characterized by oligo-ovulation/chronic anovulation, menstrual irregularities and hyperandrogenism. Objectives: The aim of this study was determined and compare the concentration PSA in 50 patients with PCOS and 50 healthy female controls. Result: The present observation showed that the mean level of PSA concentration in case (group I) was found to be (0.84 ± 0.30 ng/ml) and in control (group II) was found to be (0.53 ± 0.29 ng/ml). Statistical analysis showed that p < 0.05. Conclusion: The PSA concentration in PCOS patient was found to be higher than that of healthy controls, and the difference was statistically significant. A comparatively elevated PSA level in PCOS women as compared to normal women is an indication of hyperandrogenism.

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Additional details

Dates

Accepted
2023-11-13

References

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