Formulation and Evaluation of Anti-Microbial Agent in Various Dosage Forms by Using Ethnopharmacological Selected Indian Medicinal Plants (Solanum xanthocarpum, Adhatoda vasica nees, Oscimum sanctum)
Authors/Creators
- 1. Research Scholar, Bhupal Nobles' University, Department of Pharmacy, Udaipur
- 2. Professor, Bhupal Nobles' University, Department of Pharmacy, Udaipur
Description
The foundation of the herbal medication business is the ethnomedical values of plants. In order to create herbal
medications with minimal side effects, India has contributed its expertise in traditional system medicines
(Ayurveda and Siddha). These plants have historically been utilised by tribal communities in India as extracts,
powders, or pastes to cure conditions including anti-microbial activity, cough and colds, fever, stomach, kidney,
and liver diseases, pain, inflammation, and wounds. The current study focuses on the antibacterial properties of
Indian medicinal herbs such Ocimum sanctum, Adhatoda vasica, and Solanum xanthocarpum. Numerous of the
long-standing ethnomedicinal applications of these plants are supported by ethnopharmacological investigations.
These three ethnomedicinal plants have yielded several phytoconstituents, some of which have exhibited
pharmacological activity through in vivo and/or in vitro tests. For herbal medicines to be used safely and
effectively, ethnomedical applications that are backed by scientific research are crucial. Using the agar-well
diffusion method and various concentrations (30%, 50%, 70%, and 100%), the antibacterial activity of the
Solanaceae family plant Solanum xanthocarpum was assessed in vitro against a number of human pathogenic
microorganisms, including Escherichia coli, Yersinia pestis, Pseudomonas aeruginosa, and Staphylococcus
aureus. In comparison to the control group, chicken flesh that had been washed with AVELE for 90 minutes had
higher sensory attribute ratings for juice and tenderness as well as a higher overall sensory quality. This study
demonstrates AVELE's ability to kill L. monocytogenes NCIM 24563 effectively, indicating that it may be
utilised as a marinade or rinse for meat preservation. The Lamiaceae family of plants includes the fragrant herb
Ocimum sanctum Linn, sometimes known as holy basil. It is a native of the tropics of Asia and Africa. To
prepare the leaves for grinding, they were detached from the stem, thoroughly cleaned in clear water, and then
dried for seven days. In order to create a uniform powder, dried leaves were ground separately in an electric
grinder. The powder produced using the "cold extraction method" was converted into ethanol, hexane, and
chloroform extract. Ocimum sanctum leaves' antibacterial effectiveness suggests that the plant has strong
antimicrobial qualities. Additionally, because ocimum is so common in India, it might be suggested as a
conveniently accessible source of antibacterial compounds in place of synthetic chemicals
Abstract (English)
The foundation of the herbal medication business is the ethnomedical values of plants. In order to create herbal
medications with minimal side effects, India has contributed its expertise in traditional system medicines
(Ayurveda and Siddha). These plants have historically been utilised by tribal communities in India as extracts,
powders, or pastes to cure conditions including anti-microbial activity, cough and colds, fever, stomach, kidney,
and liver diseases, pain, inflammation, and wounds. The current study focuses on the antibacterial properties of
Indian medicinal herbs such Ocimum sanctum, Adhatoda vasica, and Solanum xanthocarpum. Numerous of the
long-standing ethnomedicinal applications of these plants are supported by ethnopharmacological investigations.
These three ethnomedicinal plants have yielded several phytoconstituents, some of which have exhibited
pharmacological activity through in vivo and/or in vitro tests. For herbal medicines to be used safely and
effectively, ethnomedical applications that are backed by scientific research are crucial. Using the agar-well
diffusion method and various concentrations (30%, 50%, 70%, and 100%), the antibacterial activity of the
Solanaceae family plant Solanum xanthocarpum was assessed in vitro against a number of human pathogenic
microorganisms, including Escherichia coli, Yersinia pestis, Pseudomonas aeruginosa, and Staphylococcus
aureus. In comparison to the control group, chicken flesh that had been washed with AVELE for 90 minutes had
higher sensory attribute ratings for juice and tenderness as well as a higher overall sensory quality. This study
demonstrates AVELE's ability to kill L. monocytogenes NCIM 24563 effectively, indicating that it may be
utilised as a marinade or rinse for meat preservation. The Lamiaceae family of plants includes the fragrant herb
Ocimum sanctum Linn, sometimes known as holy basil. It is a native of the tropics of Asia and Africa. To
prepare the leaves for grinding, they were detached from the stem, thoroughly cleaned in clear water, and then
dried for seven days. In order to create a uniform powder, dried leaves were ground separately in an electric
grinder. The powder produced using the "cold extraction method" was converted into ethanol, hexane, and
chloroform extract. Ocimum sanctum leaves' antibacterial effectiveness suggests that the plant has strong
antimicrobial qualities. Additionally, because ocimum is so common in India, it might be suggested as a
conveniently accessible source of antibacterial compounds in place of synthetic chemicals
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Additional details
Dates
- Accepted
-
2024-01-23