An Analysis of Histomorphological Spectrum of Skin Lesions at a Tertiary Care Hospital
- 1. Associate Professor, Department of Pathology, Government K.A.P.V Medical College, Tamil Nadu
- 2. Assistant Professor, Department of Pathology, Govt. Pudukkottai Medical College, Tamil Nadu
- 3. Post Graduate, Department of Pathology, Government K.A.P.V Medical College, Tamil Nadu
Description
Background: Skin diseases encompass a wide array of pathologies influenced by genetic, environmental, and socioeconomic factors. Accurate diagnosis is paramount for effective management, with histopathological examination serving as the gold standard. Despite advances in diagnostic modalities, histopathology remains gold standard for a definitive diagnosis. Methods: The study was conducted in Department of Pathology, KAP Viswanatham Government Medical College Trichy, and Tamilnadu over a period of 1 year from July 2022 to June 2023. Skin biopsies from 169 patients of all ages were analyzed. Histopathological techniques, including routine staining and special stains, were employed for in depth analysis. Results: The study exhibited a diverse age range >50 years being most frequently affected, with a male predominance. The trunk was the most commonly affected site, followed by the extremities. Non-infectious diseases were predominant, with vesiculobullous dermatoses and spongiotic/psoriatic dermatoses being the most common. Granulomatous diseases, malignant tumors, and adnexal tumors were also observed. Leprosy emerged as the most common granulomatous lesion with Fite farraco stain positive, while squamous cell carcinoma and basal cell carcinoma were the predominant malignant tumors. Discussion: Findings were consistent with existing literature, highlighting the varied nature of skin lesions and the necessity of biopsy for accurate diagnosis. The age and sex distribution of patients, as well as the prevalence of different types of skin lesions, were discussed in relation to previous studies. Conclusion: Our study of 169 skin biopsy samples revealed a significant prevalence of infectious lesions and vesiculobullous disorders, with Leprosy and Bullous Pemphigoid being prominent. In conclusion, despite advancements in molecular and genetic techniques, histopathological analysis remains pivotal in diagnosing skin lesions and inflammatory conditions.
Abstract (English)
Background: Skin diseases encompass a wide array of pathologies influenced by genetic, environmental, and socioeconomic factors. Accurate diagnosis is paramount for effective management, with histopathological examination serving as the gold standard. Despite advances in diagnostic modalities, histopathology remains gold standard for a definitive diagnosis. Methods: The study was conducted in Department of Pathology, KAP Viswanatham Government Medical College Trichy, and Tamilnadu over a period of 1 year from July 2022 to June 2023. Skin biopsies from 169 patients of all ages were analyzed. Histopathological techniques, including routine staining and special stains, were employed for in depth analysis. Results: The study exhibited a diverse age range >50 years being most frequently affected, with a male predominance. The trunk was the most commonly affected site, followed by the extremities. Non-infectious diseases were predominant, with vesiculobullous dermatoses and spongiotic/psoriatic dermatoses being the most common. Granulomatous diseases, malignant tumors, and adnexal tumors were also observed. Leprosy emerged as the most common granulomatous lesion with Fite farraco stain positive, while squamous cell carcinoma and basal cell carcinoma were the predominant malignant tumors. Discussion: Findings were consistent with existing literature, highlighting the varied nature of skin lesions and the necessity of biopsy for accurate diagnosis. The age and sex distribution of patients, as well as the prevalence of different types of skin lesions, were discussed in relation to previous studies. Conclusion: Our study of 169 skin biopsy samples revealed a significant prevalence of infectious lesions and vesiculobullous disorders, with Leprosy and Bullous Pemphigoid being prominent. In conclusion, despite advancements in molecular and genetic techniques, histopathological analysis remains pivotal in diagnosing skin lesions and inflammatory conditions.
Files
IJPCR,Vol16,Issue3,Article165.pdf
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Additional details
Dates
- Accepted
-
2024-02-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue3,Article165.pdf
- Development Status
- Active
References
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