Bacterial and Mycological Study in Burn Patients Admitted in Gauhati Medical College and Hospital
Creators
- 1. Assistant Professor, Department of Microbiology, Lakhimpur Medical College, Assam, India
- 2. Professsor, Department of Microbiology, Assam Medical College, Dibrugarh, Assam, India
- 3. Retired Professor, Department of Plastic Surgery, Gauhati Medical College, Assam, India
Description
Background: Burn wound infection is a major public health problem and globally the most devastating form of trauma. It delays healing, causes scarring and may result in bacteraemia, sepsis or multiple-organ dysfunction syndrome leading to increased morbidity and mortality. Materials and Methods: The present study was a hospital based prospective observational study on 120 burn patients admitted to the Burn ICU. The wound swabs collected from the included patients were Gram stained & bacterial and fungal culture and sensitivity was done. Results: Out of the total 120 patients, highest 41(34.16%) belonged to the 21-30 years age bracket. Preponderance of males 62(51.66%) was more than females 58(48.33%). Flame burn was found to be the commonest form of burn injury (66.7%). Bacterial culture was positive in 104 (87%) of cases, while in 12(10%) cases fungus was isolated. 154 bacterial isolates were isolated, 131 (85%) were Gram negative while rest 23(15%) were Gram positive. Pseudomonas aeruginosa was the most common bacteria isolated from 60 (39%) samples followed by Klebsiella species 28(18%) samples. Pseudomonas aeruginosa (n=60) was mostly susceptible to Imipenem (75%) followed by Gentamicin and Tigecycline with 70% and 50% respectively. Gram positive bacterial isolates (n=23) were found to be most susceptible to Vancomycin 23(100%) and Linezolid 18(100%). Conclusion: The findings of the present study revealed that Gram negative bacilli are still predominant pathogens infecting the burn wounds in this region. Effective strict isolation techniques and infection control are thus needed to decrease the occurrence of burn wound infection.
Abstract (English)
Background: Burn wound infection is a major public health problem and globally the most devastating form of trauma. It delays healing, causes scarring and may result in bacteraemia, sepsis or multiple-organ dysfunction syndrome leading to increased morbidity and mortality. Materials and Methods: The present study was a hospital based prospective observational study on 120 burn patients admitted to the Burn ICU. The wound swabs collected from the included patients were Gram stained & bacterial and fungal culture and sensitivity was done. Results: Out of the total 120 patients, highest 41(34.16%) belonged to the 21-30 years age bracket. Preponderance of males 62(51.66%) was more than females 58(48.33%). Flame burn was found to be the commonest form of burn injury (66.7%). Bacterial culture was positive in 104 (87%) of cases, while in 12(10%) cases fungus was isolated. 154 bacterial isolates were isolated, 131 (85%) were Gram negative while rest 23(15%) were Gram positive. Pseudomonas aeruginosa was the most common bacteria isolated from 60 (39%) samples followed by Klebsiella species 28(18%) samples. Pseudomonas aeruginosa (n=60) was mostly susceptible to Imipenem (75%) followed by Gentamicin and Tigecycline with 70% and 50% respectively. Gram positive bacterial isolates (n=23) were found to be most susceptible to Vancomycin 23(100%) and Linezolid 18(100%). Conclusion: The findings of the present study revealed that Gram negative bacilli are still predominant pathogens infecting the burn wounds in this region. Effective strict isolation techniques and infection control are thus needed to decrease the occurrence of burn wound infection.
Files
IJPCR,Vol16,Issue3,Article147.pdf
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Additional details
Dates
- Accepted
-
2024-02-26
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue3,Article147.pdf
- Development Status
- Active
References
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