Effect of Psyllium Supplementation on Postprandial Glycemia and Glycemic Index of Amaranthus Chapattis in Healthy Controls and Diabetic Subjects.
Authors/Creators
- 1. Senior Demonstrator, Dept. of Biochemistry, Jhalawar Medical College, Jhalawar.
- 2. Professor, Dept. of Biochemistry, Jhalawar Medical College, Jhalawar.
- 3. Assistant Professor, Dept. of Biochemistry, Jhalawar Medical College, Jhalawar.
Description
Psyllium husk obtained from plantago ovata is high in both soluble fiber (70%) and insoluble fiber (30%). Fiber improves the control of blood glucose and delays glucose absorption. The purpose of this study was to determine glycemic index of Amaranthus chapatti and to evaluate effect of psyllium supplimentation on glycemic response of Amaranthus chapatti. Subjects were randomly selected from Jhalawar Medical College, Jhalawar to participate in a case-controlled study; ninety six subjects were included in this study, subjects were given diet counseling before the study. Amaranthus chapattis were given in 50 grams of digestible available carbohydrates as test diet-1. Same Amaranthus chapatties were given along with 5 gm of psyllium husk as test diet-2. The reference food was a solution in water (250 ml) containing 50 g glucose. In the morning, 5 times the blood was collected – on an empty stomach and 30, 60, 90 and 120 minutes after eating for both test diets and reference food for three consecutive days in healthy controls and in patients with type II diabetes. Difference in Glycemic indices of Amaranthus chapatti 95.4 + 6.6 is statistically highly significant with Amaranthus chapattis with psyllium husk 87.4 + 6.2 for healthy subjects(P < 0.0001) and for diabetic patients Amaranthus chapatti (GI- 95.9 +1.6) and for Amaranthus chapatti with psyllium husk GI – 90.8 +1.3 (P < 0.0001). Our results demonstrate values of glycemic indices for Amaranthus chapatti and evaluate effect of psyllium husk on glycemic response, addition of 5 gm of psyllium husk to test diets significantly decrease the value of glycemic index in both the groups.
Abstract (English)
Psyllium husk obtained from plantago ovata is high in both soluble fiber (70%) and insoluble fiber (30%). Fiber improves the control of blood glucose and delays glucose absorption. The purpose of this study was to determine glycemic index of Amaranthus chapatti and to evaluate effect of psyllium supplimentation on glycemic response of Amaranthus chapatti. Subjects were randomly selected from Jhalawar Medical College, Jhalawar to participate in a case-controlled study; ninety six subjects were included in this study, subjects were given diet counseling before the study. Amaranthus chapattis were given in 50 grams of digestible available carbohydrates as test diet-1. Same Amaranthus chapatties were given along with 5 gm of psyllium husk as test diet-2. The reference food was a solution in water (250 ml) containing 50 g glucose. In the morning, 5 times the blood was collected – on an empty stomach and 30, 60, 90 and 120 minutes after eating for both test diets and reference food for three consecutive days in healthy controls and in patients with type II diabetes. Difference in Glycemic indices of Amaranthus chapatti 95.4 + 6.6 is statistically highly significant with Amaranthus chapattis with psyllium husk 87.4 + 6.2 for healthy subjects(P < 0.0001) and for diabetic patients Amaranthus chapatti (GI- 95.9 +1.6) and for Amaranthus chapatti with psyllium husk GI – 90.8 +1.3 (P < 0.0001). Our results demonstrate values of glycemic indices for Amaranthus chapatti and evaluate effect of psyllium husk on glycemic response, addition of 5 gm of psyllium husk to test diets significantly decrease the value of glycemic index in both the groups.
Files
IJPCR,Vol16,Issue3,Article111.pdf
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Additional details
Dates
- Accepted
-
2024-03-05
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue3,Article111.pdf
- Development Status
- Active
References
- 1. Mehta KG, Modi R & Gupta R. Psyllium. Indian J Agron. 1976; 21: 509 –510. 2. Chandalia M, Garg A, Lutjohann D, Bergmann K, Grundy SM & Brinkle LJ. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med. 2000; 34 (2): 1392 –1398. 3. Abraham ZD & Mehta T. Three-week psyllium husk supplementation: effect on plasma cholesterol concentrations, fecal steroid excretion, and carbohydrate absorption in men. Am J Clin Nutr. 1988;47: 67– 74. 4. Bajorek S.A. and Morello C.M. Effects of Dietary Fiber and Low Glycemic Index Diet on Glucose Control in Type 2 Diabetes Mellitus. The Annals of Pharmacotherapy, 2010 November:44: 1786-1792. 5. Gorinstein S, Pawelzik E, Delgado-Licon E, Haruenkit R, Weisz M, and Trakhtenberg S "Characterisation of pseudocereal and cereal proteins by protein and amino acid analyses", Journal of the Science of Food and Agriculture, 2002; 82: 886–891. 6. Yadav S., Gupta D. K., Patil P. H., Tiwari A., & Soni, P. To Study the Pharmacotherapy of Diabetes Mellitus Type 2 Patient in Echo Health Care & Research Centre, Indore". Jour Med Resh and Health Sci, 2023; 6(2): 2389– 2397. 7. Gorinstein S, Vargas O J M, Jaramillo N O, Salas I A, Ayala A L M and Trakhtenberg S "The total polyphenols and the antioxidant potentials of some selected cereals and pseudocereals", European Food Research and Technology, 2007; 225: 321–328.8. SalcedoChavez B, OsunaCastro J, GuevaraLara F, Domnguez Domnguez J and ParedesLpez O "Optimization of the isoelectric precipitation method to obtain protein isolates from amaranth (Amaranthus cruentus) seeds", Journal of Agricultural and Food Chemistry, 2002; 50(22): 6515 – 6520. 9. Wolever TM. Effect of blood sampling schedule and method of calculating the area under the curve on validity and precision of glycaemic index values. Br J Nutr. 2004 Feb; 91 (2): 295-301. 10. Foster-Powell, K., Holt, S.H.A., & BrandMiller, J.C.International table of glycemic index and glycemic load values: 2002. American Journal of Clinical Nutrition, (2002).76, 55-56. 11. Chaturvedi A, Sarojini G, Nirmala G, Nirmalamma N, Satyanarayana D. Glycemic index of grain amaranth, wheat and rice in NIDDM subjects Plant Foods Hum Nutr. 1997; 50(2):171-8. 12. Thummakomma, K., & Meda, P. (). Effect of cooking on bioactive compounds in pulses. IJCS, 2017; 5(6), 460-463. 13. Wolever TM, Vuksan V, Eshuis H, Spadafora P, Peterson RD, Chao ES, Storey ML & Jenkins DJ. Effect of method of administration of psyllium on glycemic response and carbohydrate digestibility. J Am Coll Nutr. 1991; 10: 364 – 371. 14. Salmeron J., Ascherio A., Rimm E., et al. Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care. 1997; 20: 545-550. 15. Pastors, J.G., Blaisdell, P.W., Balm, T.K., Asplin, C.M., Pohl, S.L., Psyllium fiber reduces rise in postprandial glucose and insulin concentrations in patients with non-insulindependent diabetes. American Journal of Clinical Nutrition. 1991; 53: 1431–1435. 16. Frati Munari, A.C., Benitez Pinto, W., Raul Ariza Andraca, C., Casarrubias, M., 1998. Lowering glycemic index of food by acarbose and plantago psyllium mucilage. Archives of Medical Researches. 1998; 29: 137–141. 17. Morán M.R., Romero F.G., -Burciaga G.L., () Lipid- and Glucose-Lowering Efficacy of Plantago Psyllium in Type II Diabetes. Journal of Diabetes and Its Complications, 1998; 12: 273-278. 18. Ziai S.A., Larijani B., AkhoondzadehS., Fakhrzadeh H., Dastpak A., Bandarian F., RezaiA., NaghdiBadi H., Emami T. Psyllium decreased serum glucose and glycosylated hemoglobin significantly in diabetic outpatients. ournal of Ethnopharmacology. 2005; 152(3): 202-207.