An Observational Study to Assess the Lipid Profile of Decompensated Chronic Liver Disease: A Hospital-Based Assessment

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Abstract (English)

Aim: The aim of the present study was to assess the lipid profile of Decompensated chronic liver disease.
Methods: This observational study was carried out amongst 50 Decompensated chronic liver disease patients that
fulfils the inclusion and exclusion criteria and attended the gastroenterology OPD of IGIMS, Patna, Bihar, India.
Results: 43 (86%) were male and 7 (14%) were female. The age range was from 16 to 76. The average age of the
patients in the study was 48.72±12.58 yrs. 34% of the patients were between 40 and 50 years of age. 91.67 % of
the patients were alcoholic. Abdominal distension and ascites were most common presenting complaints. Pallor
was present in 32 (64%) cases. Splenomegaly was present in 24 (48%) patients of Decompensated chronic liver
disease. Renal dysfunction was present in 18 (36%) cases. Icterus was present in 12 (24%) cases. 33 (66%) of the
patients had decreased platelet count. The comparisons between lipid profile of Decompensated chronic liver
disease patients and healthy controls was significant (p<0.05).
Conclusion: Lipid abnormalities are commonly seen in patients with Decompensated chronic liver disease and
screening for the same is essential for intervention with appropriate treatment to prevent adverse cardiovascular
events. The levels of serum total cholesterol, TG, LDL and HDL in patients with Decompensated chronic liver
disease are related to the advancement in Decompensated chronic liver disease. It helps in diagnosis of severity
of liver disease and also acts as a good prognostic sign.