Published March 30, 2024 | Version v1
Journal article Open

Surgical Outcomes of Indolent Oral Verrucous Carcinoma Patients and Their Long Term Follow Up

  • 1. Assistant Professor, Department of Surgical Oncology, St Johns Medical College Hospital, Bengaluru, Karnataka, India
  • 2. Assistant Professor, Department of Surgical Oncology, ESIC Medical College and PGIMSR and Model Hospital, Rajajinagar, Bengaluru, Karnataka, India
  • 3. Professor, Department of Surgical Oncology, St Johns Medical College Hospital, Bengaluru, Karnataka, India

Description

Background and Objectives: Oral verrucous carcinomas are uncommon tumours and they have favourable
outcomes. They have a long latency period. This study was conducted to evaluate the surgical outcomes of oral
verrucous carcinoma patients in a tertiary cancer hospital in South India.
Methods: This retrospective study was conducted in biopsy proven oral verrucous carcinoma patients who
underwent treatment at the surgical oncology department of a tertiary care center in south India, from January
2014 to December 2020. The patients were followed up until December 2023.
Results: 133 patients underwent surgery for oral carcinoma during the study period. Of these, 8 patients had
oral verrucous cancer. The mean age of presentation was 55.3 years. Buccal mucosa was the most common
subsite affected, seen in 6 patients. Three patients had pT1, four patients had pT2, and one patient had pT3.
Reexcision was done in two patients. None of our patients had recurrence in the follow up period.
Conclusion: Verrucous carcinoma is characterised by inherently favourable prognosis. It displays local
aggressive behavior and uncommon regional or distant metastasis. Surgical excision with adequate margin is the
most effective and standard treatment. There should be special emphasis on close follow up in view of high
recurrence.

Abstract (English)

Background and Objectives: Oral verrucous carcinomas are uncommon tumours and they have favourable
outcomes. They have a long latency period. This study was conducted to evaluate the surgical outcomes of oral
verrucous carcinoma patients in a tertiary cancer hospital in South India.
Methods: This retrospective study was conducted in biopsy proven oral verrucous carcinoma patients who
underwent treatment at the surgical oncology department of a tertiary care center in south India, from January
2014 to December 2020. The patients were followed up until December 2023.
Results: 133 patients underwent surgery for oral carcinoma during the study period. Of these, 8 patients had
oral verrucous cancer. The mean age of presentation was 55.3 years. Buccal mucosa was the most common
subsite affected, seen in 6 patients. Three patients had pT1, four patients had pT2, and one patient had pT3.
Reexcision was done in two patients. None of our patients had recurrence in the follow up period.
Conclusion: Verrucous carcinoma is characterised by inherently favourable prognosis. It displays local
aggressive behavior and uncommon regional or distant metastasis. Surgical excision with adequate margin is the
most effective and standard treatment. There should be special emphasis on close follow up in view of high
recurrence.

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Additional details

Dates

Accepted
2024-02-16