Published April 5, 2024 | Version v1
Dataset Open

Adult neurogenesis improves spatial information encoding in the mouse hippocampus - RC

Description

In vivo two-photon imaging dataset for Frechou et al. "Adult neurogenesis improves spatial information encoding in the mouse hippocampus"

This dataset includes data from mice that were housed in a regular cage (RC). 

For each recording we included raw imaging data consisting of:

  • Individual frames (.tif files) from 3 consecutive 3 min Ca2+ imaging movies (which were concatenated for analysis)
  • Microscope settings metadata (Experiment.xml)
  • Mouse location data (Episode001.h5 in SyncData folder) containing rotary encoder and RFID data

Some analyzed data is also included:

  • Suite2p analysis data (Suite2p folder)
  • fluorescence.npy contains raw fluorescence data (the F output of Suite2p data extraction). Rows are individual cells and columns are frames (i.e. timepoints) acquired at 15.253 Hz.
  • positions.npy contains the position of the mouse on the treadmill belt indexed from 0 to 100.

Both NumPy(.npy) files are the output of the Preprocessing.py code, part of the analysis pipeline used for data analysis in the original publication, which can be found at https://github.com/GoncalvesLab/Frechou-et-al-Neurogenesis

Refer to the original publication for additional information. The sex of individual mice is as follows:

Group Mouse # Sex
RC M1 M
  M2 M
  M3 M
  M4 F
  M5 F

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