Supplementary data for "BS012, a mixture of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia extracts, ameliorates allergic asthma via suppression of Th2-mediated immune response and apoptosis"

Supplementary materials

Figure S1: Effects of BS012 on plasma metabolites in OVA-induced asthma mice. The levels of altered metabolites related to (A) amino acid metabolism, (B) glycerophospholipid acid metabolism, and (C) sphingolipid metabolism. (D) The alteration of lactic acid, citric acid, oxohexenoic acid changed by OVA-induction and BS012 administration. The graphs depict mean ± SEM of normalized relative abundance, n = 5; #p < 0.05 vs. Control group; *p < 0.05, **p < 0.01 vs. OVA-induced group.

Figure S2: Effects of BS012 on lung tissue metabolites in OVA-induced asthma mice. The levels of altered metabolites related to (A) glycerolipid metabolism, (B) fatty acid metabolism, (C) purine metabolism, and (D) glycerophospholipid metabolism changed by OVA-induction and BS012 administration. The graphs depict mean ± SEM of normalized relative abundance, n = 5; #p < 0.05 vs. Control group; *p < 0.05, **p < 0.01 vs. OVA-induced group.

Table S1: Antibodies used for flow analysis

Table S2: List of identified metabolites altered in plasma from OVA-induced asthma mice with BS012 administration

Table S3: List of identified metabolites altered in lung tissue from OVA-induced asthma mice with BS012 administration