WEBINAR: MaveDB: discovery and interpretation of high-throughput functional assay data

This record includes training materials associated with the Australian BioCommons webinar ‘MaveDB: discovery and interpretation of high-throughput functional assay data’. This webinar took place on 26 March 2024.

Event description

Multiplexed assays of variant effect (MAVEs) are a family of experimental techniques that measure all single amino acid or single nucleotide changes in a gene or other functional element. MaveDB is an international community database that enables discovery and reuse of data from these experiments. It provides a platform for integrating large-scale measurements of sequence variant impact with applications that can be used to interpret the data for basic and clinical research.

In this webinar we consider: 

• What are MAVEs and how are the experiments performed?

• How much MAVE data is available in MaveDB and how is it organised?

• Who can submit datasets to MaveDB?

• What are some of the clinical applications for MAVEs and how is the data being used to understand patient variants?

Speaker: Dr Alan Rubin, Senior Research Officer, WEHI 

Host: Dr Melissa Burke, Australian BioCommons

Materials

Materials are shared under a Creative Commons Attribution 4.0 International agreement unless otherwise specified and were current at the time of the event.

Files and materials included in this record:

• Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc.

• Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file.

• MAVEDB_slides: A PDF copy of the slides presented during the webinar.

Materials shared elsewhere:

A recording of this webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/BXGQ2IuDnGE