Published March 28, 2024 | Version v1
Dataset Open

Comparative membrane proteomic analysis of Tritrichomonas foetus isolates (non filtered Data Sets)

Creators

  • 1. Laboratorio de Biología Molecular, Inmunología y Microbiología (LaBIM), Instituto Multidisciplinario de Salud, Tecnología y Desarrollo (IMSaTeD), CONICET-UNSE, Santiago del Estero, Argentina
  • 2. Facultad de Ciencias Médicas (FCM-UNSE), Santiago del Estero, Argentina
  • 3. Laboratorio de Parasitología Molecular, Instituto Tecnológico Chascomús (INTECH), CONICET-UNSAM, Chascomús B7130IWA, Argentina
  • 4. Escuela de Bio y Nanotecnologías (UNSAM)

Contributors

  • 1. Laboratorio de Biología Molecular, Inmunología y Microbiología (LaBIM), Instituto Multidisciplinario de Salud, Tecnología y Desarrollo (IMSaTeD), CONICET-UNSE, Santiago del Estero, Argentina
  • 2. Facultad de Ciencias Médicas (FCM-UNSE), Santiago del Estero, Argentina
  • 3. Facultad de Agronomía y Agroindustrias (FAyA-UNSE), Santiago del Estero, Argentina
  • 4. Laboratorio de Parásitos Anaerobios, Instituto Tecnológico Chascomús (INTECH), CONICET-UNSAM, Chascomús B7130IWA, Argentina
  • 5. Escuela de Bio y Nanotecnologías (UNSAM)

Description

Tritrichomonas foetus is a flagellated and anaerobic parasite able to infect cattle and felines. Despite its prevalence, there is no effective standardized or legal treatment for T. foetus-infected cattle; the vaccination still has limited success in mitigating infections and reducing abortion risk; and nowadays, the diagnosis of T. foetus presents important limitations in terms of sensitivity and specificity in bovines. Here, we characterize the plasma membrane proteome of T. foetus and identify proteins that are represented in different isolates of this protozoan.  Raw proteomics data sets from MALDI-TOF Mass Spectrometry presented here corresponds to six T. foetus isolates (Tf0-Tf5). For Tf2 isolate also five membrane fractions are presented (f1-f5).  

Series information

Tables is organized as follows:

Accession: unique identifier assigned to the protein by the database used to generate the report.
Description: protein name unique to the identifier that appears in the accession column.
Score: Displays the protein score, which is the sum of the individual peptide scores.
Coverage: Shows the percentage of the protein sequence covered by the identified peptides.
Peptides: Shows the number of peptide sequences unique to a group of proteins.
PSMs: Peptide Spectrum Matches.
Proteins: Shows the number of proteins identified in the protein group of a reference protein.
Confidence: level of confidence associated with the peptide sequence.
Sequence: amino acids compose the peptide.
ProteinGroupAccessions: unique identifiers (accessions) of all reference proteins from all protein groups that include this peptide sequence.
Modifications: static and dynamic modifications identified in the peptide.
XCorr: calculates the cross-correlation score for all candidate peptides in the queried database.
Charge: Shows the charge status of the peptide.
MH+ (Da): Shows the protonated monoisotopic mass of the peptides, in daltons.
m/z (Da): Shows the mass-charge relationship of the precursor ion, in daltons.
RT (min): Shows the retention time of the HPLC column when the peptide was observed, in minutes.
MissedCleavages: Displays the number of cleavage sites in a peptide sequence that were not cleaved by a cleavage reagent (enzyme). 

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