STRUCTURE OF SARS-COV-2 AND MEDICAL SIGNIFICANCE OF PROTEINS

The article is devoted to the structural structure of the SARS-CoV-2 virus, studying its pathogenetic properties, analyzing the role of the immune system, as well as the disorders it causes in the human body. In early December 2019, the first cases of pneumonia of unknown origin were identified in Wuhan, Hubei Province, China. The SARS-CoV-2 coronavirus is a characteristic enveloped RNA-containing virus with "crown"-shaped processes, the main structural proteins of which are the nucleocapsid protein and the receptor-binding transmembrane protein S, which causes infection of epithelial cells of the respiratory tract mucosa. Both proteins are considered highly immunogenic antigens for humans. C-19 hyperinflammation can cause cytopenia, coagulopathy, tissue damage, liver dysfunction and macrophage activation, vasculitis, and sepsis. Also, excessive production of cytokines can lead to multiple organ failure and eventually death. Based on the results of the research, we decided that the role of structural molecules in the pathogenesis of coronavirus infection is important, and people who received the vaccine produced against this virus experienced this disease more easily and recovered quickly. In the treatment of this pathology, the use of components of vaccines and promising ligands is appropriate.