Patents of Successfully Marketed Drugs Obtained from Phyto-Glycoside Sources and their Biological Action: A review
- 1. P. G. Department of Botany, Dada Patil Mahavidyalaya Karjat, Ahmednagar, Maharashtra, India.
- 2. P. G. Department of Botany, Dada Patil Mahavidyalaya Karjat, Ahmednagar, Maharashtra, India.
Description
Natural products and their structural analogues have historically made a major
contribution to pharmacotherapy, especially for cancer and infectious diseases.
Nevertheless, natural products like phytoglycosides also present challenges for drug
discovery, such as technical barriers to screening, isolation, characterization and
optimization, which contributed to a decline in their pursuit by the pharmaceutical
industry from the 1990s onwards. In recent years, several technological and scientific
developments including improved analytical tools, genome mining and engineering
strategies, and microbial culturing advances are addressing such challenges and opening
up new opportunities in drug discovery. Consequently, interest in natural products such
as phytoglycosides as drug leads is being revitalized, particularly for tackling
antimicrobial resistance. Here, we summarize recent technological developments that are
enabling natural product-based drug discovery, highlight patent of successfully marketed
drugs and discuss their biological action.
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Additional details
Dates
- Issued
-
2024-02-25Book Chapter
References
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