Published March 7, 2024 | Version v1
Dataset Open

Characterization of the tumor-immune microenvironment in hepatocellular carcinoma patients undergoing immune checkpoint inhibitor therapy by highly multiplexed imaging mass cytometry

  • 1. University Medical Center Freiburg
  • 1. ROR icon University Medical Center Freiburg
  • 2. Humanitas University
  • 3. IRCCS Humanitas Research Hospital
  • 4. Imperial College London

Description

Imaging mass cytometry data of 42 HCC patients that received immune checkpoint inhibtor therapy after tumor biopsy or resection. 

  • ICI_img_normalized: Preprocessed and normalized multistack .tiff images. Each stack represents one channel. Channel annotations are stored in the ICICohort_panel.csv file.
  • ICI_cellmasks: Masks identifying individual cells on the images.
  • ICI_stromamasks: Masks identifying stromal and parenchymal regions on the image.
  • ICICohort_panel.csv: table containing channel information (metal tag and marker).

Patient etadata may be found in the supplementary table 3 of DOI 10.1136/gutjnl-2024-332837.

Files

HCC_ICICohort.zip

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Additional details

Related works

Is published in
Journal article: 10.1136/gutjnl-2024-332837 (DOI)