Personalized Therapies for Atrial Fibrillation. A Translational Approach
Published February 29, 2024 | Version 1.0
Dataset Open

Impedance Reconstruction of Non-transmural Cardiac Fibrosis

Creators

  • 1. ROR icon Karlsruhe Institute of Technology
  • 2. Universidad Politécnica de Valencia
  • 3. Karlsruhe Institute of Technology (KIT)
  • 4. ROR icon Städtisches Klinikum Karlsruhe

Description

In this dataset we can find geometrical setups that served as an input to carry simulations with openCARP and EIDORS. The setup consists of a Lasso with point electrodes placed on patch of tissue and embedded in a box of blood. The tissue simulates a myocardium that can be either fully healthy, fully scarred, or healthy with a 8-mm width line of scar tissue.
In addition, the voltage and local impedance maps obtained as results are included.
Two kinds of simulations were performed: reconstruction the forward injection of a 5µA current at 14.6kHz with EIDORS, and the electrical wave propagation with openCARP.
For the impedance reconstruction, a four electrode circuit was always used, meaning that two electrodes were part of the injecting pattern and a potential difference was measured between another two. The stimulating pair were sequentially changed among all pairs of neighbouring electrodes, whereas the rest of them contributed to the measurement.
The voltage maps were computed taking the recovered EGMs from the electrode positions.
 

Data structure

  • inputGeometries: 24 vtk files representing the input setup for simulations. The file names are of the form imageXX_append_cleanToGrid_LOCATION, where XX is a number among 06, 11, 52, and 55, and LOCATION refers to the position in z-axis (transmural, endo-, midmyo-, epicardio).
  • results:
    • BidomainSimulations: the extracellular potentials of each electrical propagation simulation using the Courtemanche model are saved in each of the 16 folders. All the corresponding outputs from a pseudobidomain openCARP simulation are located in each folder.
      • 2023-04-16_image06_endo_00
      • 2023-04-16_image06_epi_00
      • 2023-04-16_image06_mid_00
      • 2023-04-16_image06_transmural_00
      • 2023-04-16_image11_endo_00
      • 2023-04-16_image11_epi_00
      • 2023-04-16_image11_mid_00
      • 2023-04-16_image11_transmural_00
      • 2023-04-16_image52_endo_00
      • 2023-04-16_image52_epi_00
      • 2023-04-16_image52_mid_00
      • 2023-04-16_image52_transmural_00
      • 2023-04-16_image55_endo_00
      • 2023-04-16_image55_epi_00
      • 2023-04-16_image55_mid_00
      • 2023-04-16_image55_transmural_00
    • ImpedanceSimulations: mat and vtk files corresponding to either local electrical impedance reconstruction simulation. The file names are of the form imageXX_append_cleanToGrid_LOCATION, where XX is a number among 06, 11, 52, and 55, and LOCATION refers to the position in z-axis (transmural, endo-, midmyo-, epicardio). 

Files

Impedance_Reconstruction_NonTransmural.zip

Files (2.3 GB)

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Additional details

Related works

Is described by
Conference paper: 10.22489/CinC.2023.283 (DOI)

Funding

PersonalizeAF – Personalized Therapies for Atrial Fibrillation. A Translational Approach 860974
European Commission
MICROCARD – Numerical modeling of cardiac electrophysiology at the cellular scale 955495
European Commission

Dates

Available
2024-02-29