Unintentional bursectomy of chick by Bruce Glick accidentally exposed bursal function grabbed wide reputation while Pioneer of bursa Hieronymus Fabricius Italian anatomist remained under mist

While dissecting young birds we might have detected a chestnut-size, sac-like organ located at the terminal portion of hind gut, dorsal to the rectum, anterior to the sacrum communicating with the posterior portion of the cloaca by a short duct, known as bursa of Fabricius. It is arguably true that birds and mammals are evolved from reptiles yet this unique organ never been detected in any other animal species including reptilian ancestors. Scientific community is highly indebted to chicken species that has provided a unique and precious model or else we could have failed to study basic immunology what we have explored today. In this regard unlike mammal avian immunology is a fascinating subject for several unusual features like devoid of encapsulated lymph nodes (Nochi et al., 2018) and development of B lymphocytes in bursa instead of bone marrow which will be discussed in the later part of my discussion. In recent time we have gathered enough information about bursa and its role in humoral immunity in avian species.