Published February 23, 2024 | Version 1.0
Dataset Open

Data for "A hippocampus-accumbens code guides goal-directed appetitive behavior"

  • 1. Leibniz-Institut für Neurobiologie Bibliothek
  • 2. Deutsches Zentrum für Neurodegenerative Erkrankungen

Contributors

Data collector:

Supervisor:

  • 1. Leibniz Institute for Neurobiology

Description

This dataset represents the source data for the manuscript "A hippocampus-accumbens code guides goal-directed appetitive behavior" by Barnstedt, Mocellin, and Remy. All files are saved as dataframes with pandas (v1.4.3, using 'blosc' compression for H5).

It contains the following files:

ArchT.feather

Dataframe containing all source behavioural data for mice expressing ArchT in NAc-projecting dHPC neurons. 10 mice in ArchT/EYFP groups are tested for 8 days on a head-fixed spatial reward learning task. 100 Hz temporal resolution.
behaviour.h5 Dataframe containing all source behavioural data accompanying calcium imaging, collected from analogue signals and camera signals, downsampled to 15/30 Hz to match imaging temporal resolution.
C.h5 Deconvolved calcium signals from 5372 dHPC pyramidal neurons recorded at 15/30 Hz in Thy1-GCaMP6s mice. Data collected with two-photon imaging and extracted using CaImAn.
ChR.feather Dataframe containing all source behavioural data for mice expressing ChR2 in dHPC axons in NAc. 7 mice in ChR2/EYFP groups are tested over several days while naive and during a head-fixed spatial reward learning task. 75 Hz temporal resolution.
comps.feather Dataframe containing one row per neuron, showing diverse neuronal features.
psth_ds.feather Dataframe with peri-stimulus time histograms of calcium activity around lick onsets.
S.h5 Deconvolved calcium events from 5372 dHPC pyramidal neurons recorded at 15/30 Hz in Thy1-GCaMP6s mice. Data collected with two-photon imaging and extracted using CaImAn.
success_comreward.feather Dataframe showing successful behavioural trials with percentage of dHPC-/dHPC-->NAc neurons with place field centers near the reward zone.
training.feather Dataframe containing all source behavioural data without calcium imaging, collected from analogue signals and camera signals, collected at 25/75 Hz from 18 mice.

Files

Files (957.5 MB)

Name Size Download all
md5:34648ade2a449b5479fd1e3dc1d0d390
277.7 MB Download
md5:f724305e90c78bd0b426718eef706f18
12.1 MB Download
md5:db113eb8b49e09fd4f4d80a6158fbbed
394.5 MB Download
md5:b6abbdd061de1660d56949597ae86ca5
153.5 MB Download
md5:fa3de8b1f720db4d574256aca549f031
1.7 MB Download
md5:05b02595f566075c29ca0cae893699f4
9.7 MB Download
md5:ae7b3577926e1fc7d298359cad2ea8f3
45.1 MB Download
md5:d01f9a1365d25d74dd5e3a3adeab5e94
4.0 kB Download
md5:af0ba3ff435a3f4ba497e3ab94d2b440
63.2 MB Download

Additional details

Related works

Is source of
Preprint: 10.1101/2023.03.09.531869 (DOI)

Software

Repository URL
https://github.com/obarnstedt/dHPC-NAc
Programming language
Jupyter Notebook, Python
Development Status
Inactive