Published February 24, 2024
| Version v3
Journal article
Open
SMOC1: A Target Enabling Package
Authors/Creators
- Li, Qianjin1
- Gospodinova, Katerina2
- Ajith, Ishita2
- Siciliano, Benjamin1
- Halabelian, Levon3
- Wiley, Jesse4
- Cary, Gregory5
- YCharOS6
- Bakshi, Souvika2
- Nwakamma, Richard1
- Zoeller, Elizabeth1
- Betarbet, Ranjita1
- Katis, Vittorio2
- Levey, Allan1
- Wen, Zhexing1
- Brennan, Paul2
- Fu, Haian1
- The Emory-Sage-SGC TREAT-AD Center
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1.
Emory University
- 2. Alzheimer's Research UK Oxford Drug Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, United Kingdom
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3.
University of Toronto
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4.
Sage Bionetworks
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5.
Jackson Laboratory
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6.
McGill University
Description
SMOC1 (SPARC related modular calcium binding 1) is an amyloid plaque associated protein that is implicated
in AD pathogenesis and may function as a viable biomarker of disease progression. However, little is known
about the biological role of SMOC1 in the central nervous system, nor what role it may play in AD
pathogenesis. The aim of this project is to produce TEP reagents to help further understand the biology of
SMOC1 in Alzheimer’s disease.
Files
TREAT-AD Basic TEP_SMOC1_v2_Final.pdf
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